Section for Climate Therapy, Department of Rheumatology, Oslo University Hospital, Rikshospitalet, PO Box 4950 Nydalen, 0424 Oslo, Norway.
J Rehabil Med. 2011 May;43(6):534-42. doi: 10.2340/16501977-0804.
To investigate the sustained effect of a rehabilitation programme for patients with ankylosing spondylitis, and to compare the effect of this intervention given in a Mediterranean vs a Norwegian setting.
A total of 107 patients with ankylosing spondylitis applying for rehabilitation were randomized to a 4-week inpatient rehabilitation programme in a Mediterranean country or in Norway. The participants were evaluated clinically before and after the rehabilitation period (week 0 and 4) and in week 16. The ASsessments in Ankylosing Spondylitis working group's Improvement Criteria (ASAS-IC), and tests of spinal mobility and physical capacity were used to measure treatment response.
An ASAS20 improvement was still present at week 16 in 50% of the patients treated in a Mediterranean and 23% in a Norwegian centre (p = 0.006). The tests of spinal mobility, physical capacity, and almost all patient's assessments of health status (ASAS-IC components) were still improved at week 16 after therapy in both climatic settings. While the improvements in physical capacity were comparable, the spinal mobility and ASAS-IC components improved more, and improvements were sustained longer, after rehabilitation in a Mediterranean setting.
Patients with ankylosing spondylitis benefit from a 4-week rehabilitation programme in Norway, but even more so from a similar programme in a Mediterranean setting.
研究强直性脊柱炎患者康复计划的持续效果，并比较在地中海和挪威环境中进行这种干预的效果。
共有 107 名强直性脊柱炎患者申请在地中海国家或挪威进行为期 4 周的住院康复计划。参与者在康复期前后（第 0 周和第 4 周）和第 16 周进行临床评估。使用强直性脊柱炎评估工作组的改善标准（ASAS-IC）以及脊柱活动度和身体能力测试来衡量治疗反应。
在接受地中海治疗的患者中，有 50%在第 16 周仍有 ASAS20 改善，而在挪威中心接受治疗的患者中，这一比例为 23%（p=0.006）。在两种气候环境下，治疗后第 16 周，脊柱活动度、身体能力以及几乎所有患者的健康状况评估（ASAS-IC 组成部分）仍有改善。虽然身体能力的改善相当，但在地中海环境中进行康复治疗后，脊柱活动度和 ASAS-IC 组成部分的改善更多，并且持续时间更长。
强直性脊柱炎患者在挪威接受 4 周的康复计划会受益，但在类似的地中海环境中受益更多。
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