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伴桥本甲状腺炎的重症肌无力和吉兰-巴雷综合征的时间巧合。

Temporal coincidence of myasthenia gravis and Guillain Barré syndrome associated with Hashimoto thyroiditis.

机构信息

Department of Neurology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, 230022 Hefei, China.

出版信息

Neurol Sci. 2011 Jun;32(3):515-7. doi: 10.1007/s10072-011-0579-3. Epub 2011 Apr 14.

DOI:10.1007/s10072-011-0579-3
PMID:21491098
Abstract

Both myasthenia gravis (MG) and Guillain Barré syndrome (GBS) are autoimmune diseases leading to muscle weakness, while the temporal coincidence of MG and GBS is rare. Here, we report a case of MG and GBS, as well as Hashimoto's thyroiditis, for the first time. All these diseases were relieved by immunomodulatory therapy, which suggested abnormal regulation of the autoimmune system might be the cause in our case. In addition, MG was not diagnosed at first from the initial symptom of unilateral lateral rectus muscle palsy.

摘要

重症肌无力(MG)和吉兰-巴雷综合征(GBS)均为导致肌肉无力的自身免疫性疾病,而 MG 和 GBS 的同时发生较为罕见。在此,我们首次报道 1 例 MG 和 GBS 合并桥本甲状腺炎患者。所有这些疾病均通过免疫调节治疗得到缓解,这表明异常的自身免疫调节可能是导致该病例的原因。此外,最初单侧外直肌瘫痪的症状并未诊断出 MG。

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本文引用的文献

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2
The co-occurrence of serologically proven myasthenia gravis and Miller Fisher/Guillain Barré overlap syndrome: a case report.血清学确诊的重症肌无力与米勒·费雪/格林-巴利重叠综合征并存:一例报告
J Neurol Sci. 2009 Jan 15;276(1-2):187-8. doi: 10.1016/j.jns.2008.08.019. Epub 2008 Sep 19.
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Myasthenia gravis and Guillain-Barré syndrome occurring simultaneously in the same patient.
格林-巴利综合征合并重症肌无力:三例报告及文献复习
Medicine (Baltimore). 2019 Nov;98(47):e18104. doi: 10.1097/MD.0000000000018104.
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Asymmetric pattern in generalized myasthenia gravis: A case report.重症肌无力全身型的不对称模式:一例报告
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