Department of Psychology, Ohio State University, Columbus, OH 43210, USA.
Neural Comput. 2011 Jul;23(7):1790-820. doi: 10.1162/NECO_a_00135. Epub 2011 Apr 14.
Simultaneous recordings were collected from between two and four buildup neurons from the left and right superior colliculi in rhesus monkeys in a simple two-choice brightness discrimination task. The monkeys were required to move their eyes to one of two response targets to indicate their decision. Neurons were identified whose receptive fields were centered on the response targets. The functional role of inhibition was examined by conditionalizing firing rate on a high versus low rate in target neurons 90 ms to 30 ms before the saccade and examining the firing rate in both contralateral and ipsilateral neurons. Two models with racing diffusion processes were fit to the behavioral data, and the same analysis was performed on simulated paths in the diffusion processes that have been found to represent firing rate. The results produce converging evidence for the lack of a functional role for inhibition between neural populations corresponding to the two decisions.
在简单的双色辨别任务中，对恒河猴左右上丘的两到四个积累神经元进行同步记录。猴子需要将眼睛移动到两个反应目标中的一个来表示他们的决定。确定了其感受野集中在反应目标上的神经元。通过在 90 到 30 毫秒前的扫视时将目标神经元的高与低放电率条件化，并检查对侧和同侧神经元的放电率，来检查抑制的功能作用。将两个具有竞争扩散过程的模型拟合到行为数据中，并在扩散过程中发现代表放电率的模拟路径上执行相同的分析。结果为缺乏对应于两个决策的神经群体之间抑制作用的功能作用提供了收敛证据。
