合成乏氧发光介孔硅纳米粒子用于药物同步递送和成像。
Synthesis of oxygen-deficient luminescent mesoporous silica nanoparticles for synchronous drug delivery and imaging.
机构信息
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-Xi Rd., Shanghai 200050, PR China.
出版信息
Chem Commun (Camb). 2011 Jul 28;47(28):7947-9. doi: 10.1039/c1cc11479d. Epub 2011 Apr 18.
PMID:21499640
Abstract
Oxygen-deficient luminescent mesoporous silica nanoparticles with uniform morphology/size and integrated mesoporosity-luminescent property in a single nanoparticle are successfully synthesized by a bottom-up self-assembly route followed by a post-calcination process, and can be used to facilely load/deliver drugs into cells and luminescently image cells.
摘要
通过自下而上的自组装路线和随后的煅烧后处理过程，成功合成了具有均匀形态/尺寸和集成介孔-发光性能的缺氧发光介孔硅纳米粒子，并且可以用于简便地将药物载入/递送至细胞并对细胞进行发光成像。
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