Vaughan Christine, Wagner Glenn, Miyashiro Lisa, Ryan Gery, Scott James D
RAND Corporation, Santa Monica, CA, USA,
J Int Assoc Physicians AIDS Care (Chic). 2011 May-Jun;10(3):176-82. doi: 10.1177/1545109711399365. Epub 2011 Apr 20.
Previous research suggests that routinization of medication-taking behavior promotes antiretroviral therapy (ART) adherence. The current study explored the nature of medication-taking routines in the home environment, where medication is most often taken, to identify home-based cues for taking ART. Qualitative interviews were conducted in the homes of 31 HIV-positive adult males in the United States with varying levels of adherence problems. Interviews were audiotaped and transcribed. Content analysis was performed to elicit themes from the text and further categorize responses. Patients with more routinized medication-taking behavior reported fewer adherence problems. Home-based medication-taking triggers that were especially common among patients who reported fewer adherence problems included meals, pillboxes, time of day, and visual cues. Findings characterize the nature of home-based medication-taking routines and suggest the potential utility of the home environment as a setting for adherence interventions.
先前的研究表明，服药行为的常规化可促进抗逆转录病毒疗法（ART）的依从性。当前的研究探讨了在家中（最常服药的环境）服药常规的本质，以确定在家中服用ART的提示因素。对美国31名有不同程度依从性问题的HIV阳性成年男性进行了定性访谈。访谈进行了录音和转录。进行内容分析以从文本中引出主题并进一步对回答进行分类。服药行为更常规化的患者报告的依从性问题较少。在报告依从性问题较少的患者中特别常见的家庭服药触发因素包括用餐、药盒、一天中的时间和视觉提示。研究结果描述了家庭服药常规的本质，并表明家庭环境作为依从性干预场所的潜在效用。
