Favorov M O, Shakhgil'dian I V, Iashina T L, Onishchenko G G, Firsova S N, Eraliev A E
Zh Mikrobiol Epidemiol Immunobiol. 1990 Nov(11):37-44.
The results of epidemiological, clinical and laboratory studies revealed that the sharp rise of morbidity in viral hepatitides in Osh Province, the Kirghiz SSR in autumn 1987 was caused by hepatitis non A, non B virus with fecal-oral transmission. At this period the results of the enzyme immunoassay showed the absence of the markers of hepatitides A, B and Delta in 72.2% of viral hepatitis patients. Hepatitis non A, non B occurred only in 2.4% of viral hepatitis patients of preschool age (of these, 83.3% had hepatitis A) and was diagnosed in autumn 1987 in 50% of the patients aged 7-14 years and in 97.4% of the patients aged 15-29 years (in the latter age group 95-98% of the patients had IgG to hepatitis A virus in their blood). The appearance of the outbreak of the above-mentioned infection in Kirghizia is linked with the water route of the transmission of the infective agent. The epidemiological and clinical signs, characteristic of fecal-oral hepatitis non A, non B in Kirghizia, were not different from those registered earlier in other republics of the Central Asia and could be used for the identification of this infection.
流行病学、临床和实验室研究结果显示，1987年秋季吉尔吉斯苏维埃社会主义共和国奥什州病毒性肝炎发病率急剧上升是由经粪-口传播的非甲非乙型肝炎病毒引起的。在此期间，酶免疫测定结果显示，72.2%的病毒性肝炎患者体内不存在甲型、乙型和丁型肝炎标志物。非甲非乙型肝炎仅发生在2.4%的学龄前病毒性肝炎患者中（其中83.3%患有甲型肝炎），1987年秋季，7至14岁患者中有50%被诊断为此病，15至29岁患者中有97.4%被诊断为此病（在后一年龄组中，95%至98%的患者血液中含有甲型肝炎病毒IgG）。吉尔吉斯斯坦上述感染疫情的出现与感染源的水传播途径有关。吉尔吉斯斯坦经粪-口传播的非甲非乙型肝炎的流行病学和临床症状与中亚其他共和国早些时候记录的症状并无不同，可用于识别这种感染。
