Favorov M O, Kuzin S N, Iashina T L, Zairov G K, Gurov A V, Shavakhabov Sh Sh, Buriev A Ia, Zhantemirov B U, Shakhgil'dian I V, Ketiladze E S
Vopr Virusol. 1989 Jul-Aug;34(4):436-42.
An increase in the incidence of viral hepatitis was observed in the autumn of 1986 in one of the districts of southern Uzbekistan. The clinico-epidemiological data and highly sensitive tests for hepatitis A (HA) and B (HB) markers showed the absence of HB infection in most of the patients and prevalence of HA among children. In 68.7% of the patients, non-A-non-B hepatitis with fecal-oral mechanism of transmission of the infection was diagnosed. The bulk of HnAnB patients consisted of adults of 20-29 years. Pregnant women experience severe forms of the disease. Solid-phase enzyme-immunoassays and immune electron microscopy revealed in one fecal specimen from patients the antigen of non-A-non-B hepatitis serologically identical to that causing a rise in the incidence in northern Turkmenia in 1984-1985.
1986年秋季，在乌兹别克斯坦南部的一个地区观察到病毒性肝炎发病率上升。临床流行病学数据以及针对甲型肝炎（HA）和乙型肝炎（HB）标志物的高灵敏度检测表明，大多数患者不存在HB感染，且甲型肝炎在儿童中流行。在68.7%的患者中，诊断出具有粪-口传播机制的非甲非乙型肝炎。大多数非甲非乙型肝炎患者为20至29岁的成年人。孕妇会经历该疾病的严重形式。固相酶免疫测定和免疫电子显微镜检查在患者的一份粪便标本中发现了非甲非乙型肝炎抗原，其血清学特征与1984年至1985年在土库曼斯坦北部导致发病率上升的抗原相同。
