Oregon Research Institute, Eugene, OR, USA.
Am J Clin Nutr. 2011 Jul;94(1):7-11. doi: 10.3945/ajcn.110.010025. Epub 2011 Apr 27.
Weight suppression, which reflects the difference between the highest previous weight and current weight, has predicted future increases in body mass index (BMI) and bulimic pathology; however, the mechanisms underlying these predictive effects are unclear.
The current study sought to test whether weight suppression predicts future increases in BMI and bulimic symptoms and whether suppressed resting metabolic rate (RMR) and suppressed total energy expenditure (TEE) drive these relations.
A randomly selected subsample of 91 young women in their first year of college with body image concerns completed an RMR assessment--a doubly labeled water assessment of TEE--and provided data on weight suppression and change in BMI and bulimic symptoms over a 6-mo follow-up period.
Weight suppression predicted future increases in BMI and correlated inversely with suppressed RMR and TEE, yet this predictive effect did not decrease when suppressed RMR and TEE were controlled for. Weight suppression, however, did not predict future increases in bulimic symptoms.
The results provide additional evidence that weight suppression predicts future increases in BMI but not in bulimic symptoms. Weight suppression showed moderate relations with suppressed RMR and TEE, but these variables do not appear to drive the predictive effect on future increases in BMI. This trial was registered at clinicaltrials.gov as NCT00433680.
体重抑制反映了既往最高体重与当前体重之间的差异，它可以预测体重指数（BMI）和暴食障碍的未来增长；然而，这些预测效应的机制尚不清楚。
本研究旨在测试体重抑制是否可以预测 BMI 和暴食症状的未来增加，以及抑制的静息代谢率（RMR）和抑制的总能量消耗（TEE）是否会导致这些关系。
在大学一年级有身体意象问题的 91 名年轻女性中，随机选择了一个子样本，她们完成了 RMR 评估——TEE 的双标记水评估——并在 6 个月的随访期间提供了体重抑制和 BMI 及暴食症状变化的数据。
体重抑制预测了 BMI 的未来增长，与抑制的 RMR 和 TEE 呈负相关，但当控制抑制的 RMR 和 TEE 时，这种预测效应并没有降低。然而，体重抑制并不能预测未来暴食症状的增加。
结果提供了额外的证据，表明体重抑制可以预测 BMI 的未来增加，但不能预测暴食症状的未来增加。体重抑制与抑制的 RMR 和 TEE 呈中度相关，但这些变量似乎不会影响 BMI 未来增加的预测效应。本试验在 clinicaltrials.gov 上注册为 NCT00433680。
