Fukai Katsuhiko, Morioka Kazuki, Yoshida Kazuo
Exotic Diseases Research Station, National Institute of Animal Health, Tokyo 187–0022, Japan.
J Vet Med Sci. 2011 Sep;73(9):1207-10. doi: 10.1292/jvms.11-0063. Epub 2011 May 2.
In this study, we carried out an experimental infection in pigs using a foot-and-mouth disease virus isolated from the 2010 epidemic in Japan to analyze the clinical manifestation, antibody response and virus shedding patterns in pigs. We found that the virus was virulent in pigs, producing a synchronous disease in the inoculated pigs and efficient spread to direct contact pigs. These results are useful for epidemiologically investigating the 2010 epidemic in Japan and improving the measures for controlling possible future FMD outbreaks in Japan or elsewhere.
在本研究中，我们使用从2010年日本疫情中分离出的口蹄疫病毒对猪进行了实验性感染，以分析猪的临床表现、抗体反应和病毒排泄模式。我们发现该病毒对猪具有致病性，在接种猪中引发同步疾病，并有效地传播给直接接触的猪。这些结果有助于对2010年日本疫情进行流行病学调查，并改进日本或其他地区未来控制可能的口蹄疫疫情的措施。
