Gunja Naren
The Children's Hospital at Westmead, Westmead, Australia.
J Paediatr Child Health. 2012 Jul;48(7):560-6. doi: 10.1111/j.1440-1754.2011.02082.x. Epub 2011 Apr 29.
Adolescents are experimenting with recreational drugs on a regular basis, particularly at social gatherings such as parties, raves and mass events. A combination of reduced fluid intake, physical activity and drug-induced hyperthermia leads to complications such as heat stroke, delirium and potentially death. The clinician needs to be aware of the variety of pharmacologically active substances available in the recreational marketplace in order to diagnose and manage these patients. Recreational misadventure, because of incorrect dosage or mixing multiple substances, is a common reason for teenagers presenting to hospital with toxidromes. Death from club drug overdose is more likely to be associated with suicidal intent, related risky behaviour and trauma, as well as the inherent toxicity of the drug itself. Although many teenagers are concerned about 'drink spiking' with club drugs, the most common agent causing drink spiking incidents is ethanol.
青少年经常尝试使用消遣性药物，尤其是在派对、锐舞派对和大型活动等社交场合。液体摄入量减少、身体活动以及药物引起的体温过高共同导致中暑、谵妄等并发症，甚至可能导致死亡。临床医生需要了解消遣性市场上可用的各种药理活性物质，以便诊断和治疗这些患者。由于用药剂量不当或混合多种物质导致的消遣性药物意外是青少年因中毒综合征入院的常见原因。俱乐部药物过量致死更可能与自杀意图、相关危险行为和创伤以及药物本身的固有毒性有关。尽管许多青少年担心在饮料中被掺入俱乐部药物，但导致饮料中被下药事件的最常见因素是乙醇。
