Faculty of Letters, Atomi University, Saitama, Japan.
Biopsychosoc Med. 2011 May 2;5:5. doi: 10.1186/1751-0759-5-5.
Some women with depressive disorders experience severe premenstrual symptoms. However, there have been few studies in which premenstrual symptoms in women suffering from depressive disorders were assessed. In this study, we aimed to investigate premenstrual symptoms in women with depressive disorders using the premenstrual dysphoric disorder (PMDD) scale.
We administered questionnaires to 65 Japanese female outpatients who had been diagnosed with a major depressive disorder or dysthymic disorder and to 303 healthy women as control subjects. The questionnaire consisted of items on demographics and the PMDD scale, which was modified from the premenstrual symptoms screening tool (PSST) developed by Steiner et al. (Arch Womens Ment Health 2003, 6:203-209).
Twenty-eight women (43.1%) with depressive disorder fulfilled certain items of the PMDD scale. These women are considered to have coexisting PMDD and a depressive disorder, or to have premenstrual exacerbation (PME) of a depressive disorder. On the other hand, 18 women (5.9%) in the control group were diagnosed as having PMDD. The depressive disorder group who fulfilled the PMDD criteria had more knowledge of the term premenstrual syndrome (PMS) and took more actions to attenuate premenstrual symptoms than the control group with PMDD.
Our findings demonstrated that the occurrence of severe premenstrual symptoms is much higher in women with depressive disorders than in healthy subjects. This is partially due to this group containing women with PME, but mainly due to it containing women with PMDD. The higher percentage of PMDD suggests similarity between PMDD and other depressive disorders. Furthermore, educating healthy Japanese women and women with depressive disorders about premenstrual symptoms and evidence-based treatment for them is necessary.
一些患有抑郁症的女性经历严重的经前症状。然而，很少有研究评估患有抑郁症的女性的经前症状。在这项研究中，我们旨在使用经前烦躁障碍（PMDD）量表调查患有抑郁症的女性的经前症状。
我们向 65 名日本女性门诊患者和 303 名健康女性发放了问卷，这些女性均被诊断为重度抑郁症或心境恶劣障碍。问卷包括人口统计学和 PMDD 量表的项目，该量表是由 Steiner 等人开发的经前期症状筛查工具（PSST）改编而来。
28 名（43.1%）患有抑郁症的女性符合 PMDD 量表的某些项目。这些女性被认为同时患有 PMDD 和抑郁症，或患有抑郁症的经前期加重（PME）。另一方面，对照组中有 18 名（5.9%）女性被诊断为 PMDD。符合 PMDD 标准的抑郁障碍组比对照组中患有 PMDD 的女性更了解经前期综合征（PMS）一词，并采取更多措施来减轻经前症状。
我们的研究结果表明，患有抑郁症的女性出现严重经前症状的发生率远高于健康女性。这部分是由于该组中包含 PME 女性，但主要是由于该组中包含 PMDD 女性。PMDD 的更高比例表明 PMDD 与其他抑郁障碍相似。此外，有必要对健康的日本女性和患有抑郁症的女性进行经前症状教育，并为她们提供基于证据的治疗方法。
