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生物通信与自然基因组编辑。

Biocommunication and natural genome editing.

作者信息

Witzany Guenther

机构信息

Guenther Witzany, Telos-Philosophische Praxis, Vogelsangstrasse 18c, A-5111-Buermoos, Austria.

出版信息

World J Biol Chem. 2010 Nov 26;1(11):348-52. doi: 10.4331/wjbc.v1.i11.348.

DOI:10.4331/wjbc.v1.i11.348
PMID:21537469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3083936/
Abstract

The biocommunicative approach investigates communication processes within and among cells, tissues, organs and organisms as sign-mediated interactions, and nucleotide sequences as code, i.e. language-like text, which follows in parallel three kinds of rules: combinatorial (syntactic), context-sensitive (pragmatic), and content-specific (semantic). Natural genome editing from a biocommunicative perspective is competent agent-driven generation and integration of meaningful nucleotide sequences into pre-existing genomic content arrangements and the ability to (re-)combine and (re-)regulate them according to context-dependent (i.e. adaptational) purposes of the host organism.

摘要

生物交流方法将细胞、组织、器官和生物体内部及之间的交流过程作为符号介导的相互作用进行研究,并将核苷酸序列视为代码,即类似语言的文本,它遵循三种并行的规则:组合规则(句法规则)、上下文敏感规则(语用规则)和内容特定规则(语义规则)。从生物交流的角度来看,自然基因组编辑是由有能力的主体驱动的,将有意义的核苷酸序列生成并整合到预先存在的基因组内容排列中,并根据宿主生物体的上下文相关(即适应性)目的对其进行(重新)组合和(重新)调控的能力。

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