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两种遗传密码:活性非编码RNA的重复语法;DNA档案的非重复语法。

Two genetic codes: Repetitive syntax for active non-coding RNAs; non-repetitive syntax for the DNA archives.

作者信息

Witzany Guenther

机构信息

Telos - Philosophische Praxis, Buermoos, Austria.

出版信息

Commun Integr Biol. 2017 Mar 15;10(2):e1297352. doi: 10.1080/19420889.2017.1297352. eCollection 2017.

Abstract

Current knowledge of the RNA world indicates 2 different genetic codes being present throughout the living world. In contrast to non-coding RNAs that are built of repetitive nucleotide syntax, the sequences that serve as templates for proteins share-as main characteristics-a non-repetitive syntax. Whereas non-coding RNAs build groups that serve as regulatory tools in nearly all genetic processes, the coding sections represent the evolutionarily successful function of the genetic information storage medium. This indicates that the differences in their syntax structure are coherent with the differences of the functions they represent. Interestingly, these 2 genetic codes resemble the function of all natural languages, i.e., the repetitive non-coding sequences serve as appropriate tool for organization, coordination and regulation of group behavior, and the non-repetitive coding sequences are for conservation of instrumental constructions, plans, blueprints for complex protein-body architecture. This differentiation may help to better understand RNA group behavioral motifs.

摘要

目前对RNA世界的了解表明,整个生物界存在两种不同的遗传密码。与由重复核苷酸句法构成的非编码RNA不同,作为蛋白质模板的序列具有一个共同的主要特征,即非重复句法。非编码RNA形成的群体在几乎所有遗传过程中作为调控工具,而编码部分则代表了遗传信息存储介质在进化上成功的功能。这表明它们句法结构的差异与它们所代表的功能差异是一致的。有趣的是,这两种遗传密码类似于所有自然语言的功能,即重复的非编码序列是组织、协调和调节群体行为的合适工具,而非重复的编码序列则用于保存工具结构、计划以及复杂蛋白质体结构的蓝图。这种分化可能有助于更好地理解RNA群体行为模式。

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