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剖宫产术中预防腹膜粘连:可吸收粘连屏障有效性分析

Peritoneal adhesion prevention at cesarean section: an analysis of the effectiveness of an absorbable adhesion barrier.

作者信息

Chapa Hector O, Venegas Gonzalo, Vanduyne Charles P, Antonetti Alfred G, Sandate Jeffrey P, Silver Lori

机构信息

Women's Specialty Center, Dallas, Texas, USA.

出版信息

J Reprod Med. 2011 Mar-Apr;56(3-4):103-9.

Abstract

OBJECTIVE

To evaluate the effectiveness of an absorbable adhesion barrier utilized at cesarean delivery.

STUDY DESIGN

We performed a retrospective, two-arm cohort, chart review of primary and subsequent first repeat cesarean sections from January 1, 2006-December 31, 2009. Exclusion criteria were incomplete operative report, history of prior abdominal-pelvic surgery, pelvic inflammatory disease, chorioamnionitis, emergency cesarean delivery or use of corticosteroids within 2 weeks. Adhesion incidence/severity as well as skin incision to newborn delivery times were analyzed. Effects of peritoneal closure and suture types were examined.

RESULTS

Of 262 primary cesareans performed, 43% (N= 112) had repeat cesarean section. With barrier, 74% had no adhesions at repeat surgery, versus 22% in the no barrier group (p = 0.011). Eleven percent had grade 2 adhesions with barrier, while 64% had grade 2-3 in the no barrier group (p = 0.012). The barrier group had no grade 3 adhesions. Those with parietal peritoneal closure had less incidence (p = 0.02) and mean adhesion severity (p = 0.03); no significant difference was found per suture type. No statistical difference in time from skin incision to newborn delivery was noted between primary and barrier group (p = 0.006); those without barrier had a statistically longer delivery interval (p = 0.35).

CONCLUSION

Use of an absorbable adhesion baóóórrier reduces the incidence and severity of adhesions at cesarean.

摘要

目的

评估剖宫产术中使用可吸收粘连屏障的有效性。

研究设计

我们对2006年1月1日至2009年12月31日期间首次及后续首次重复剖宫产的病例进行了回顾性双臂队列图表审查。排除标准为手术报告不完整、既往有腹盆腔手术史、盆腔炎、绒毛膜羊膜炎、急诊剖宫产或在2周内使用过皮质类固醇。分析粘连发生率/严重程度以及皮肤切开至新生儿娩出时间。检查腹膜关闭方式和缝线类型的影响。

结果

在262例首次剖宫产中,43%(N = 112)进行了重复剖宫产。使用屏障的患者中,74%在重复手术时无粘连,而无屏障组为22%(p = 0.011)。使用屏障的患者中11%有2级粘连,而无屏障组64%有2 - 3级粘连(p = 0.012)。屏障组无3级粘连。采用壁腹膜关闭的患者粘连发生率较低(p = 0.02),平均粘连严重程度也较低(p = 0.03);不同缝线类型之间未发现显著差异。首次剖宫产组与屏障组皮肤切开至新生儿娩出时间无统计学差异(p = 0.006);无屏障组分娩间隔在统计学上更长(p = 0.35)。

结论

使用可吸收粘连屏障可降低剖宫产粘连的发生率和严重程度。

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