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黄芪多糖对阳离子牛血清白蛋白诱导的大鼠肾炎的影响

[Effects of Astragalus polysaccharide on nephritis induced by cationic bovine serum albumin in rats].

作者信息

Li Shi-Gang, Chen Yan, Zhang Yong-Qi

机构信息

Medical College, China Three Gorges University, Yichang 443002, China.

出版信息

Zhong Yao Cai. 2010 Dec;33(12):1913-6.

PMID:21548372
Abstract

OBJECTIVE

To study the effects of Astragalus polysaccharide on nephritis induced by cationic bovine serum albumin in rats.

METHODS

C-BSA induced nephritis model was utilized in rats. The effects of Astragalus polysaccharide on this model were investigated.

RESULTS

Proteinuria of the Astragalus polysaccharide group was alleviated. The pathological damages of the Astragalus polysaccharide group were less severe in comparison with the model group. The Astragalus polysaccharide group could improve erythrocyte immune function and increase the CD35 and CD44s contents of red blood cells.

CONCLUSION

Astragalus polysaccharide exerts a good effect in alleviating glomerular immune inflammation and improving erythrocyte immune function in the treatment of C-BSA induced nephritis.

摘要

目的

研究黄芪多糖对阳离子牛血清白蛋白诱导的大鼠肾炎的影响。

方法

采用阳离子牛血清白蛋白诱导大鼠肾炎模型,研究黄芪多糖对该模型的影响。

结果

黄芪多糖组蛋白尿减轻,与模型组相比,黄芪多糖组病理损伤较轻。黄芪多糖组可提高红细胞免疫功能,增加红细胞CD35和CD44s含量。

结论

黄芪多糖在治疗阳离子牛血清白蛋白诱导的肾炎中,对减轻肾小球免疫炎症和改善红细胞免疫功能有良好作用。

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[Effects of Astragalus polysaccharide on nephritis induced by cationic bovine serum albumin in rats].黄芪多糖对阳离子牛血清白蛋白诱导的大鼠肾炎的影响
Zhong Yao Cai. 2010 Dec;33(12):1913-6.
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Preparation and suppressive effect of astragalus polysaccharide in glomerulonephritis rats.黄芪多糖对肾小球肾炎大鼠的制备及抑制作用
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Rat bovine serum albumin (BSA) nephritis. VI. The influence of chemically altered antigen.大鼠牛血清白蛋白(BSA)肾炎。VI. 化学改变抗原的影响。
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Fucoidan inhibits the development of proteinuria in active Heymann nephritis.岩藻依聚糖可抑制活动性海曼肾炎蛋白尿的发展。
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