School of Molecular Bioscience, University of Sydney, Darlington 2006, Australia.
J Bacteriol. 2011 Jul;193(13):3399-400. doi: 10.1128/JB.05109-11. Epub 2011 May 6.
Nocardioides sp. strain JS614 grows on ethene and vinyl chloride (VC) as sole carbon and energy sources and is of interest for bioremediation and biocatalysis. Sequencing of the complete genome of JS614 provides insight into the genetic basis of alkene oxidation, supports ongoing research into the physiology and biochemistry of growth on ethene and VC, and provides biomarkers to facilitate detection of VC/ethene oxidizers in the environment. This is the first genome sequence from the genus Nocardioides and the first genome of a VC/ethene-oxidizing bacterium.
节杆菌属 Nocardioides sp. 菌株 JS614 可以以乙烯和氯乙烯 (VC) 作为唯一的碳源和能源生长,因此具有生物修复和生物催化的应用价值。JS614 的全基因组测序为烯键氧化的遗传基础提供了深入了解,支持了对乙烯和 VC 生长生理学和生物化学的持续研究,并提供了生物标志物,以促进环境中 VC/乙烯氧化菌的检测。这是第一个来自节杆菌属的基因组序列,也是第一个 VC/乙烯氧化细菌的基因组。