在化学空间会合？比较拜耳和先灵的小分子化合物库。
Rendezvous in chemical space? Comparing the small molecule compound libraries of Bayer and Schering.
机构信息
Bayer HealthCare, Lead Generation and Optimization - Medicinal Chemistry Berlin and Wuppertal, Aprather Weg 18a, D-42096 Wuppertal, Germany.
出版信息
Drug Discov Today. 2011 Jul;16(13-14):636-41. doi: 10.1016/j.drudis.2011.04.005. Epub 2011 Apr 30.
PMID:21554978
Abstract
Here, we compare the entire compound collections of Bayer HealthCare and Schering AG with respect to structural identities, similarities and physico-chemical properties. We discuss possible consequences stemming from unexpected findings in light of new collaborative models in pharmaceutical research.
摘要
在这里，我们比较了拜耳健康护理公司和先灵公司的整个化合物库，从结构同一性、相似性和物理化学性质方面进行了比较。我们根据新的药物研究合作模式，讨论了意料之外的发现可能带来的后果。
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