一种具有双重VP7血清型特异性的猪轮状病毒毒株。
A porcine rotavirus strain with dual VP7 serotype specificity.
作者信息
Nagesha H S, Huang J, Hum C P, Holmes I H
机构信息
School of Microbiology, University of Melbourne, Parkville, Victoria, Australia.
出版信息
Virology. 1990 Mar;175(1):319-22. doi: 10.1016/0042-6822(90)90215-d.
Porcine rotavirus MDR-13, which on original isolation showed a two-way antigenic relationship with human rotavirus RV-3, shows VP7 relationships with serotype G5 as well as G3 viruses upon gene reassortment. Analysis of porcine MDR-13 and the MD-UK reassortant revealed marked nucleotide and amino acid similarity of VP7 genes of these viruses with those of both serotype G3 and G5 viruses. Evolution of such a strain, possibly by sequential mutations in the VP7 gene, is discussed.
猪轮状病毒MDR-13最初分离时显示与人轮状病毒RV-3存在双向抗原关系，在基因重配后，其VP7与G5血清型以及G3病毒存在关联。对猪MDR-13和MD-UK重配体的分析表明，这些病毒的VP7基因与G3和G5血清型病毒的VP7基因在核苷酸和氨基酸上具有显著相似性。本文讨论了这种毒株可能通过VP7基因的连续突变而产生的进化过程。
Zotero 插件