Variend S
Department of Histopathology, Children's Hospital, Sheffield, U.K.
Early Hum Dev. 1990 Jan;21(1):31-40. doi: 10.1016/0378-3782(90)90108-u.
Nine hundred and fifty-one paediatric autopsies showed 24 cases in which the parotid contained cytomegalovirus-(CMV-) type inclusions. Parotid inclusions were found only during the first two years after birth. Of those with parotid inclusions, 15 showed microglial nodules in the brainstem and/or cerebellum. All the infants with microglial nodules were less than 6 months old. Only four infants without parotid inclusions showed microglial nodules. In just over half of the cases with parotid inclusions and microglial nodules death had been recorded as cases of sudden infant death syndrome. Whether there was any connection between the cause of death and microglial nodules remains uncertain as the microglial nodules were usually sparse and widely distributed. Some theories are proposed in this regard and in connection with those dying with parotid inclusions in the absence of microglial nodules. Until the question is finally resolved it may be prudent to view separately all cases of unexplained sudden death in infancy with evidence of CMV infection.
951例儿科尸检显示，有24例腮腺中含有巨细胞病毒（CMV）型包涵体。仅在出生后的头两年发现了腮腺包涵体。在有腮腺包涵体的病例中，15例在脑干和/或小脑中出现了小胶质结节。所有有小胶质结节的婴儿均小于6个月。只有4例没有腮腺包涵体的婴儿出现了小胶质结节。在超过半数有腮腺包涵体和小胶质结节的病例中，死亡被记录为婴儿猝死综合征病例。由于小胶质结节通常稀疏且分布广泛，死亡原因与小胶质结节之间是否存在任何关联仍不确定。针对这一点以及那些在没有小胶质结节的情况下死于腮腺包涵体的病例，提出了一些理论。在这个问题最终解决之前，谨慎的做法可能是将所有有CMV感染证据的不明原因婴儿猝死病例单独看待。
