Department of Physical Education and Sport, University of Extremadura, Cáceres, Badajoz, Spain.
Eur J Appl Physiol. 2012 Jan;112(1):357-64. doi: 10.1007/s00421-011-1982-4. Epub 2011 May 11.
The purpose of this study was to elucidate the effect of 6 months of aerobic exercise on urinary excretion of female steroid hormones in pre and postmenopausal women and to check the basal values of urinary steroid. To this end, 20 premenopausal (age 45.56 ± 4.06 years) and 20 postmenopausal (age 52.27 ± 3.80 years) women, all sedentary, were studied before and after a supervised 6-month exercise training program (at 60-70% of maximal heart rate, 60 min/day, 3 days/week), based on aerobic dance. The exercise included standing on one leg, squatting, walking, and touching their heels. Before and after the program, anthropometric data and VO(2max) were measured and urine samples were collected and analyzed by gas chromatography/mass spectrometry (GC/Q-MS). Both, pre and postmenopausal women, improved their VO(2max) after the aerobic exercise program. Regarding the urinary steroids, on the one hand, important differences were observed between urinary estrogens and progestagens in pre and postmenopausal women in basal values. Estrone (P < 0.05), pregnanediol (P < 0.01), pregnanetriol (P < 0.05), and estriol (P < 0.01) levels were lower in postmenopausal women than in premenopausal women. On the other hand, the aerobic exercise program did not affect postmenopausal women in the same way as premenopausal women. After the exercise program, no changes in urinary steroid levels were observed in premenopausal women. However, the aerobic exercise program caused an increase in urinary excretion of pregnanediol (P < 0.05) and pregnanetriol (P < 0.05) in postmenopausal women.
这项研究的目的是阐明 6 个月的有氧运动对绝经前和绝经后妇女尿中女性类固醇激素排泄的影响，并检查尿类固醇的基础值。为此，对 20 名绝经前（年龄 45.56 ± 4.06 岁）和 20 名绝经后（年龄 52.27 ± 3.80 岁）久坐的女性进行了研究，她们在经过监督的 6 个月的运动训练方案（最大心率的 60-70%，60 分钟/天，每周 3 天）前后进行了研究，该方案基于有氧舞蹈。运动包括单腿站立、下蹲、行走和触摸脚跟。在计划前后，测量了人体测量数据和最大摄氧量（VO 2 max），收集并通过气相色谱/质谱法（GC/Q-MS）分析了尿液样本。有氧运动方案后，绝经前和绝经后妇女的 VO 2 max 均得到改善。关于尿类固醇，一方面，绝经前和绝经后妇女的基础值中雌酮（P <0.05）、孕烷二醇（P <0.01）、孕烷三醇（P <0.05）和雌三醇（P <0.01）水平存在显著差异。另一方面，该运动方案对绝经后妇女的影响与绝经前妇女不同。运动方案后，绝经前妇女的尿类固醇水平没有变化。然而，有氧运动方案导致绝经后妇女尿中孕烷二醇（P <0.05）和孕烷三醇（P <0.05）的排泄增加。
