Yoon Jae-Ryang, Ha Gi-Chul, Ko Kwang-Jun, Kang Seol-Jung
Department of Physical Education, Korea National Sport University, Seoul, Korea.
Department of Sports Medicine, National Fitness Center, Seoul, Korea.
J Exerc Rehabil. 2018 Dec 27;14(6):1032-1040. doi: 10.12965/jer.1836446.223. eCollection 2018 Dec.
This study aims to identify the effects of exercise type on estrogen, tumor markers, immune function, antioxidant function, and physical fitness in postmenopausal obese women. The subjects were 30 post-menopausal obese women with body fat percentage higher than 30%. Participants were divided into aerobic exercise group (n=10; age, 53.70±3.37 years), resistance exercise group (n=10; age, 52.20±2.15 years), and control group (n=10; age, 52.50±2.68 years). Estrogen and growth hormone showed no significant difference in the aerobic exercise group, resistance exercise group, and control group. Tumor marker alpha-fetoprotein was increased in the aerobic exercise, resistance exercise, and control groups (<0.01). The metabolic syndrome risk factor was decreased in the aerobic and resistance exercise groups, which was shown by the reduction of weight (<0.001), body fat percentage (<0.001), waist circumference (<0.05), and increase of high density lipoprotein-cholesterol (<0.001). natural killer cell activity was increased in the aerobic exercise group, resistance exercise group, and control group (<0.001). Oxidative stress was decreased in the aerobic exercise group, resistance exercise group, and control group (<0.001). Maximum oxygen uptake was increased in the aerobic and resistance exercise groups, but aerobic exercise was more effective (<0.05). Knee isokinetic extensor muscle was increased in both the aerobic and resistance exercise groups (<0.001). Aerobic and resistance exercise of postmenopausal obese women can be considered an effective intervention program to prevent metabolic syndrome and improve physical fitness.
本研究旨在确定运动类型对绝经后肥胖女性雌激素、肿瘤标志物、免疫功能、抗氧化功能和身体素质的影响。研究对象为30名绝经后肥胖女性，其体脂百分比高于30%。参与者被分为有氧运动组（n = 10；年龄，53.70±3.37岁）、抗阻运动组（n = 10；年龄，52.20±2.15岁）和对照组（n = 10；年龄，52.50±2.68岁）。有氧运动组、抗阻运动组和对照组的雌激素和生长激素无显著差异。有氧运动组、抗阻运动组和对照组的肿瘤标志物甲胎蛋白均升高（<0.01）。有氧运动组和抗阻运动组的代谢综合征风险因素降低，表现为体重减轻（<0.001）、体脂百分比降低（<0.001）、腰围减小（<0.05）以及高密度脂蛋白胆固醇升高（<0.001）。有氧运动组、抗阻运动组和对照组的自然杀伤细胞活性均升高（<0.001）。有氧运动组、抗阻运动组和对照组的氧化应激均降低（<0.001）。有氧运动组和抗阻运动组的最大摄氧量均增加，但有氧运动更有效（<0.05）。有氧运动组和抗阻运动组的膝关节等速伸肌均增加（<0.001）。绝经后肥胖女性的有氧运动和抗阻运动可被视为预防代谢综合征和改善身体素质的有效干预方案。
