Verma R K, Ziegler D K, Kepes J J
Department of Neurology, University of Kansas Medical Center, Kansas City 66103.
Neurology. 1990 Mar;40(3 Pt 1):544-6. doi: 10.1212/wnl.40.3_part_1.544.
A young homosexual man presented with slowly progressive weakness and diffuse fasciculations. Muscle biopsy was compatible with clinical diagnosis of motor neuron disease. The patient died from opportunistic infections related to acquired immunodeficiency syndrome. Autopsy revealed evidence of myelopathy, patchy fiber loss from anterior nerve roots, marked demyelination within intramuscular twigs of peripheral nerves, and primary myopathic features superimposed on advanced neurogenic atrophy of the skeletal muscles.
一名年轻的同性恋男性出现缓慢进展的肌无力和弥漫性肌束震颤。肌肉活检结果与运动神经元病的临床诊断相符。该患者死于与获得性免疫缺陷综合征相关的机会性感染。尸检发现存在脊髓病证据、前神经根散在性纤维丢失、周围神经肌内小分支明显脱髓鞘，以及叠加在骨骼肌晚期神经源性萎缩之上的原发性肌病特征。
