Gleeson M J, Thompson A S, Mehta S, Griffith D P
Scott Department of Urology, Baylor College of Medicine, Houston, Texas.
Urology. 1990 Mar;35(3):231-4. doi: 10.1016/0090-4295(90)80038-o.
Seventeen hypercalciuria patients (8 control, 9 treatment) with a history of urolithiasis were randomly selected to receive low-calcium, low-oxalate diets with or without the addition of 30 g of dietary fiber as unprocessed wheat bran. Diet alone resulted in a 5.6 percent decrease in calciuria compared with a 23.5 percent decrease with the addition of the fiber. The addition of hydrochlorothiazide and potassium citrate further reduced calciuria by 40.4 percent and 34.5 percent, respectively. Oxaluria was decreased 21.4 percent by diet alone compared with 3.9 percent in the diet and fiber treatment group. Patient compliance to diets was good, and no complications resulted from fiber intake.
十七名有尿石症病史的高钙尿症患者（8名对照，9名治疗）被随机选取，接受低钙、低草酸饮食，部分患者饮食中添加30克未加工麦麸形式的膳食纤维。仅饮食干预使尿钙排泄量降低了5.6%，而添加膳食纤维后降低了23.5%。加用氢氯噻嗪和枸橼酸钾后，尿钙排泄量分别进一步降低了40.4%和34.5%。仅饮食干预使草酸尿排泄量降低了21.4%，而饮食加膳食纤维治疗组降低了3.9%。患者对饮食的依从性良好，摄入膳食纤维未引发并发症。
