Swart Sanne, Wildschut Marleen, Draijer Nel, Langeland Willemien, Smit Jan H
GGZ Friesland, Borniastraat 34b, Leeuwarden, 8934 AD, the Netherlands.
Department of Psychiatry and EMGO Institute, Vrije University Medical Center/GGZinGeest, Amsterdam, the Netherlands.
BMC Psychiatry. 2017 May 10;17(1):173. doi: 10.1186/s12888-017-1339-6.
Trauma-related disorders and personality disorders are prevalent in survivors of chronic childhood trauma and neglect. Both conditions have serious consequences for patients, their families, society and public health and a high risk of development of chronicity. However, information on the long term course trajectories is lacking and predictors of course outcome in survivors of chronic childhood traumatization are unknown. The first aim of the current study is to identify two-year course trajectories of pathology in patients with trauma-related disorders and personality disorders. The second aim is to examine predictors of the course, including demographics, clinical characteristics and comorbidities.
METHODS/DESIGN: The study is a naturalistic two-year follow-up of 150 patients consecutively admitted to the trauma treatment program and the personality disorder treatment program respectively at GGZ Friesland, a regular Dutch mental health care center. The only exclusion criterion is insufficient mastery of the Dutch language. Participants will be assessed after 2 years of treatment through measures that have been completed at baseline, including structured clinical interviews to measure childhood histories of trauma and neglect, (symptoms of) trauma-related disorders and personality disorders, and psychological questionnaire measures (e.g., general psychopathology, depressive symptoms and personality features). In addition, participants will complete an evaluation questionnaire to assess medication prescribed and treatment (s) received outside GGZ Friesland between baseline and follow-up. Information about (psychological and pharmacological) treatment received at GGZ Friesland during the follow-up period will be collected from patient files.
This study provides insight in the two-year course of (comorbid) trauma-related disorders and personality disorders. Identifying predictors of the course of trauma-related and personality disorders will allow to differentiate clinical profiles and will offer indicators for treatment.
创伤相关障碍和人格障碍在童年长期遭受创伤和忽视的幸存者中很常见。这两种情况都会给患者、其家庭、社会和公共卫生带来严重后果，且有很高的慢性化发展风险。然而，目前缺乏关于长期病程轨迹的信息，童年长期受创伤幸存者病程结果的预测因素也尚不明确。本研究的首要目的是确定创伤相关障碍和人格障碍患者的两年病程轨迹。第二个目的是研究病程的预测因素，包括人口统计学特征、临床特征和共病情况。
方法/设计：本研究是一项对150名患者进行的自然主义两年随访研究，这些患者分别连续入住荷兰一家普通精神卫生保健中心弗里斯兰心理健康中心的创伤治疗项目和人格障碍治疗项目。唯一的排除标准是荷兰语掌握不足。在治疗2年后，将通过在基线时完成的测量方法对参与者进行评估，包括结构化临床访谈，以测量童年创伤和忽视史、创伤相关障碍和人格障碍（的症状），以及心理问卷测量（如一般精神病理学、抑郁症状和人格特征）。此外，参与者将完成一份评估问卷，以评估在基线和随访期间在弗里斯兰心理健康中心以外所开的药物和接受的治疗。随访期间在弗里斯兰心理健康中心接受的（心理和药物）治疗信息将从患者档案中收集。
本研究有助于深入了解（共病的）创伤相关障碍和人格障碍的两年病程。确定创伤相关障碍和人格障碍病程的预测因素将有助于区分临床特征，并为治疗提供指标。
