Science and Technology Branch, Environment Canada , Burlington, ON, L7R 4A6, Canada.
Environ Sci Technol. 2011 Jun 15;45(12):5088-98. doi: 10.1021/es2003028. Epub 2011 May 17.
Dechlorane Plus (DP) is a high production volume, chlorinated flame retardant. Despite its long production history, it was only recently found in the environment. The first "sightings" of DP were in the North American Great Lakes, but subsequent work has indicated that DP is a global contaminant. For example, DP has recently been detected along a pole-to-pole transect of the Atlantic Ocean. Although it was initially thought that DP was produced only in North America, another DP production plant has recently been identified in China. During the course of characterizing DP in the environment, other "DP-like" compounds were identified. These DP analogs, some created from impurities contained in the starting materials during DP's synthesis, have also been detected globally. Screening-level modeling data are in general agreement with available environmental measurements, suggesting that DP and it analogs may be persistent, bioaccumulative, and subject to long-range transport and that these chemicals may be candidates for Annex D evaluation under the United Nations Stockholm Convention on Persistent Organic Pollutants. However, more research is required to better quantify the emissions, exposures, and toxicological effects of DP and its analogs in the environment. In particular, there is a need to obtain more monitoring, bioaccumulation, degradation rate, and toxicity information.
得克隆（DP）是一种高产量、含氯的阻燃剂。尽管它的生产历史悠久，但直到最近才在环境中被发现。DP 的首次“发现”是在北美的五大湖，但随后的研究表明 DP 是一种全球性的污染物。例如，DP 最近已在沿大西洋的一条从极点到极点的横截线上被检测到。尽管最初认为 DP 仅在北美生产，但最近在中国又发现了另一个 DP 生产厂。在对环境中的 DP 进行特征描述的过程中，还鉴定出了其他“DP 类似物”。这些 DP 类似物中的一些是在 DP 合成过程中由原料中的杂质产生的，它们也在全球范围内被检测到。基于筛选水平的建模数据与现有的环境测量数据基本一致，这表明 DP 及其类似物可能具有持久性、生物蓄积性和长距离迁移性，并且这些化学物质可能是《关于持久性有机污染物的斯德哥尔摩公约》附件 D 评估的候选物质。然而，需要开展更多的研究来更好地量化 DP 及其类似物在环境中的排放、暴露和毒理学效应。特别是需要获得更多的监测、生物蓄积、降解速率和毒性信息。
