Department of Dermatology, Kurume University School of Medicine and Kurume Institute of Cutaneous Cell Biology, Kurume, Fukuoka, Japan.
J Dermatol. 2011 Oct;38(10):993-5. doi: 10.1111/j.1346-8138.2011.01242.x. Epub 2011 May 19.
Tako-no-Suidashi ointment (TSO) is an old Japanese over-the-counter drug, used for the drainage of infectious pustular disease, such as furuncles, carbuncles and infectious atheroma, although whether it works well or not is unknown. The ingredients of the TSO compound commonly include rapeseed oil, gum rosin, wood rosin, Japanese wax, paraffin, petrolatum, copper sulfate, Peru balsam, acetic acid, salicylic acid and trace amounts of Guinea green B. We report a case of contact dermatitis in a 38-year-old Japanese woman caused by TSO. The patient presented to our hospital with pruritic erythema on her left cheek. In order to remove a subcutaneous tumor, she had applied TSO 4 days prior to presentation. Clinical examination showed a well-demarcated exudative erythematous macule with yellowish crusts and scales on her left cheek. Patch testing showed a positive reaction to TSO (++), gum rosin (++) and wood rosin (++) at 72 h. As TSO includes highly allergenic material, caution should be made in applying this topical therapy.
塔可诺苏达希软膏（TSO）是一种日本传统的非处方药物，用于引流传染性脓疱病，如疖、痈和传染性脂瘤，尽管其疗效并不明确。TSO 复方的成分通常包括菜籽油、松香、木松香、日本蜡、石蜡、凡士林、硫酸铜、秘鲁香脂、醋酸、水杨酸和微量的几内亚绿 B。我们报告了一例由 TSO 引起的 38 岁日本女性接触性皮炎。患者因左侧脸颊瘙痒性红斑就诊于我院。为了切除皮下肿瘤，她在就诊前 4 天涂抹了 TSO。临床检查显示左侧脸颊边界清楚的渗出性红斑性斑疹，伴有黄色结痂和鳞屑。斑贴试验显示 TSO（++）、松香（++）和木松香（++）在 72 小时后呈阳性反应。由于 TSO 含有高度致敏物质，在应用这种局部治疗时应谨慎。
