Assisted Fertility Services, Community Health Network, 8040 Clearvista Parkway, Indianapolis, IN 46256, USA.
Reprod Biomed Online. 2011 Sep;23(3):314-22. doi: 10.1016/j.rbmo.2010.11.019. Epub 2010 Dec 13.
The past decade has witnessed renewed interest in human oocyte cryopreservation (OCP). This article reviews the two general methods used for OCP, slow freezing and vitrification, compares the outcomes associated with each technique and discusses the factors that might influence success with OCP (such as oocyte selection or day of transfer). Based on available data, OCP offers a reliable, reproducible method for preservation of the female gamete and will find increasing application in assisted reproductive technology. Oocyte cryopreservation can provide a number of advantages to couples undergoing assisted reproduction or to women interested in fertility preservation. Two methods, slow freezing and vitrification, have been used successfully for oocyte cryopreservation. This article reviews and compares these methods, and discusses various factors that can impact upon success of oocyte cryopreservation.
过去十年，人们对人类卵母细胞冷冻保存（OCP）重新产生了兴趣。本文综述了 OCP 的两种常用方法，即慢速冷冻和玻璃化，并比较了每种技术相关的结果，讨论了可能影响 OCP 成功的因素（如卵母细胞选择或移植日）。基于现有数据，OCP 为女性配子的保存提供了一种可靠且可重复的方法，并将在辅助生殖技术中得到越来越多的应用。卵母细胞冷冻保存可为接受辅助生殖的夫妇或有生育力保存需求的女性提供多种优势。两种方法，即慢速冷冻和玻璃化，已成功应用于卵母细胞冷冻保存。本文对这两种方法进行了综述和比较，并讨论了可能影响卵母细胞冷冻保存成功的各种因素。
