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A Razor's Edge: Vascular Responses to Acute Inflammatory Lung Injury/Acute Respiratory Distress Syndrome.锋芒毕露:急性炎症性肺损伤/急性呼吸窘迫综合征的血管反应。
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Simvastatin-induced sphingosine 1-phosphate receptor 1 expression is KLF2-dependent in human lung endothelial cells.辛伐他汀诱导的1-磷酸鞘氨醇受体1表达在人肺内皮细胞中依赖于KLF2。
Pulm Circ. 2017 Mar 21;7(1):117-125. doi: 10.1177/2045893217701162. eCollection 2017 Mar.
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Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.糖皮质激素通过诱导鞘氨醇激酶1(SphK1),与炎症刺激协同作用,限制急性肺炎症。
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Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome.鞘氨醇 1-磷酸受体 3 中的功能性启动子变异与脓毒症相关急性呼吸窘迫综合征易感性相关。
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Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury.鞘氨醇-1-磷酸受体-3 是急性肺损伤的一种新型生物标志物。
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本文引用的文献

1
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.ANGPT2 基因变异与创伤相关的急性肺损伤和血浆血管生成素-2 同工型比例改变有关。
Am J Respir Crit Care Med. 2011 May 15;183(10):1344-53. doi: 10.1164/rccm.201005-0701OC. Epub 2011 Jan 21.
2
Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS.血管生成素-2基因中的遗传变异与急性呼吸窘迫综合征风险增加相关。
Intensive Care Med. 2009 Jun;35(6):1024-30. doi: 10.1007/s00134-009-1413-8. Epub 2009 Mar 7.
3
Sex-specific association of epidermal growth factor gene polymorphisms with acute respiratory distress syndrome.表皮生长因子基因多态性与急性呼吸窘迫综合征的性别特异性关联
Eur Respir J. 2009 Mar;33(3):543-50. doi: 10.1183/09031936.00091308. Epub 2008 Nov 14.
4
Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma.肌球蛋白轻链激酶基因的变异与严重创伤后急性肺损伤的发生有关。
Crit Care Med. 2008 Oct;36(10):2794-800. doi: 10.1097/ccm.0b013e318186b843.
5
Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.Toll样受体1基因多态性影响脓毒症的固有免疫反应及预后。
Am J Respir Crit Care Med. 2008 Oct 1;178(7):710-20. doi: 10.1164/rccm.200803-462OC. Epub 2008 Jul 17.
6
Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations.急性肺损伤中的巨噬细胞移动抑制因子:表达、生物标志物及相关性
Transl Res. 2007 Jul;150(1):18-29. doi: 10.1016/j.trsl.2007.02.007. Epub 2007 May 25.
7
Pre-B-cell colony-enhancing factor gene polymorphisms and risk of acute respiratory distress syndrome.前B细胞集落增强因子基因多态性与急性呼吸窘迫综合征的风险
Crit Care Med. 2007 May;35(5):1290-5. doi: 10.1097/01.CCM.0000260243.22758.4F.
8
Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators.血管生成素-2在严重脓毒症中升高:与炎症介质的相关性。
Crit Care Med. 2007 Jan;35(1):199-206. doi: 10.1097/01.CCM.0000251640.77679.D7.
9
Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury.肌球蛋白轻链激酶基因中的新型多态性赋予急性肺损伤风险。
Am J Respir Cell Mol Biol. 2006 Apr;34(4):487-95. doi: 10.1165/rcmb.2005-0404OC. Epub 2006 Jan 6.
10
Vascular endothelial growth factor gene polymorphism and acute respiratory distress syndrome.血管内皮生长因子基因多态性与急性呼吸窘迫综合征
Thorax. 2005 Mar;60(3):244-8. doi: 10.1136/thx.2004.034785.

Focusing on the flood: targeting functional polymorphisms in ALI permeability pathways.

作者信息

Garcia Joe G N

出版信息

Am J Respir Crit Care Med. 2011 May 15;183(10):1287-9. doi: 10.1164/rccm.201104-0623ED.

DOI:10.1164/rccm.201104-0623ED
PMID:21596828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3114056/
Abstract
摘要