Institute of Neuroscience and Medicine INM-2, Research Centre Jülich, Jülich, Germany.
Ann N Y Acad Sci. 2011 May;1225 Suppl 1:E94-104. doi: 10.1111/j.1749-6632.2011.05978.x.
In the context of increasing extinction rates and the potential loss of essential evolutionary biological and anthropological information, it is an important task to support efforts to prepare, preserve, and curate collections of histological brain sections; to disseminate information on such collections in the neuroscience community; and to make the collections publicly available. This review emphasizes the importance of complete, serially sectioned human brains of different ontogenetic stages as well as those of adult and old human individuals for neurobiological and medical research. Such histological sections enable microstructural analyses and anatomical evaluations of functional and structural neuroimaging data, for example, based on magnetic resonance imaging. Here, this review provides the first detailed and updated account of the content of the Stephan, Zilles, and Zilles-Amunts collections, which consist of serially sectioned and cell body- and myelin-stained histological preparations. Finally, this review will give an overview of past and recent research using these collections to increase our understanding of the detailed patterns of divergent brain evolution in primates as well as of the structural organization of the human brain.
在物种灭绝率不断上升和可能失去重要进化生物学和人类学信息的背景下，支持准备、保存和管理组织学脑切片收藏、在神经科学界传播有关此类收藏的信息以及使收藏公开的工作是一项重要任务。本综述强调了完整的、按顺序分段的不同个体发育阶段的人脑，以及成年和老年个体的人脑对于神经生物学和医学研究的重要性。这些组织学切片允许对功能和结构神经影像学数据进行微观结构分析和解剖评估，例如基于磁共振成像。在这里，本综述首次详细和更新了 Stephan、Zilles 和 Zilles-Amunts 收藏的内容，这些收藏由按顺序分段和细胞体及髓鞘染色的组织学制剂组成。最后，本综述将概述过去和最近使用这些收藏的研究，以增加我们对灵长类动物大脑进化差异模式以及人类大脑结构组织的详细理解。
