排卵前卵泡卵泡液中的雌激素、雄激素和孕激素：通过与稳定同位素稀释相关的气相色谱/质谱法进行鉴定和定量。
Estrogens, androgens, and progestins in follicular fluid from preovulatory follicles: identification and quantification by gas chromatography/mass spectrometry associated with stable isotope dilution.
作者信息
Dehennin L
机构信息
Fondation de Recherche en Hormonologie, Fresnes, France.
出版信息
Steroids. 1990 Apr;55(4):181-4. doi: 10.1016/0039-128x(90)90108-n.
The synthesis and use of stable isotope-labeled analogs of various steroids have made it possible to undertake a study of follicular fluid (FF) aspirated from mature and preovulatory follicles. Our previous results have been brought together here in order to review quantitative work done by gas chromatography-mass spectrometry. A positive gradient between peripheral plasma and FF concentrations of a steroid suggests the possibility of ovarian biosynthesis. This is particularly relevant to the catecholestrogens, 19-norsteroids, and some corticosteroids.
各种类固醇稳定同位素标记类似物的合成与应用，使得对从成熟和排卵前卵泡抽吸的卵泡液（FF）进行研究成为可能。我们之前的研究结果汇总于此，以便回顾通过气相色谱 - 质谱法完成的定量工作。类固醇在外周血浆和卵泡液浓度之间的正梯度表明存在卵巢生物合成的可能性。这对于儿茶酚雌激素、19 - 去甲类固醇和一些皮质类固醇尤为重要。
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