Department of Endocrinology Center for Sexology and Gender Problems, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.
Eur J Endocrinol. 2011 Aug;165(2):331-7. doi: 10.1530/EJE-11-0250. Epub 2011 May 20.
To describe sexual desire in female-to-male transsexual persons post sex reassignment surgery (SRS). The associations between serum androgen levels and sexual desire are examined.
Single center cross-sectional study.
Forty-five female-to-male transsexual persons post SRS completed a standardized questionnaire assessing sexual desire (Sexual Desire Inventory). In addition, participants were asked questions on sexual desire before starting hormone treatment and having SRS. Serum levels of testosterone, LH and sex hormone-binding globulin were measured on fasting morning serum samples.
In retrospect, 73.9% of the participants reported an increase in sexual desire after hormone treatment and SRS. Solitary sexual desire scores were significantly correlated with frequency of masturbation (r=0.835; P<0.001), whereas frequency of sexual intercourse with a partner was not. No direct associations were found between testosterone and solitary or dyadic sexual desire. However, ANOVA showed an independent effect of LH on solitary sexual desire (P<0.001). Post hoc analysis revealed that female-to-male transsexual persons with elevated levels of LH, indicating suboptimal testosterone therapy, reported significantly lower solitary sexual desire levels (than those with low LH levels; P=0.007). Suppressed LH levels were also associated with having a higher need for sexual activities (P=0.009) and a higher frequency of excessive sexual desire (P=0.007).
Most female-to-male transsexual persons report on a marked increase in sexual desire after testosterone treatment and SRS. No direct associations between levels of testosterone and solitary or dyadic sexual desire were found. However, measures of sexual desire were inversely associated with LH levels.
描述接受性别重置手术后的女性-男性跨性别者的性欲。检查血清雄激素水平与性欲之间的关系。
单中心横断面研究。
45 名接受性别重置手术的女性-男性跨性别者完成了评估性欲的标准化问卷（性欲量表）。此外，还询问了参与者在开始激素治疗和接受性别重置手术之前的性欲问题。空腹晨血样检测血清睾酮、LH 和性激素结合球蛋白水平。
回顾性分析显示，73.9%的参与者报告在激素治疗和性别重置手术后性欲增加。单一性欲评分与自慰频率显著相关（r=0.835；P<0.001），而与性伴侣的性交频率无关。睾酮与单一或双重性欲之间没有直接关联。然而，方差分析显示 LH 对单一性欲有独立影响（P<0.001）。事后分析显示，LH 水平升高（提示睾酮治疗不足）的女性-男性跨性别者报告的单一性欲水平显著较低（与 LH 水平较低者相比；P=0.007）。LH 水平受抑制也与性活动需求较高（P=0.009）和性欲过度频率较高（P=0.007）有关。
大多数女性-男性跨性别者在接受睾酮治疗和性别重置手术后报告性欲明显增加。未发现睾酮水平与单一或双重性欲之间存在直接关联。然而，性欲测量值与 LH 水平呈负相关。
