Bihl Florian, Castelli Damiano, Marincola Francesco, Dodd Roger Y, Brander Christian
Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
J Transl Med. 2007 Jun 6;5:25. doi: 10.1186/1479-5876-5-25.
Although the risk of transfusion-transmitted infections today is lower than ever, the supply of safe blood products remains subject to contamination with known and yet to be identified human pathogens. Only continuous improvement and implementation of donor selection, sensitive screening tests and effective inactivation procedures can ensure the elimination, or at least reduction, of the risk of acquiring transfusion transmitted infections. In addition, ongoing education and up-to-date information regarding infectious agents that are potentially transmitted via blood components is necessary to promote the reporting of adverse events, an important component of transfusion transmitted disease surveillance. Thus, the collaboration of all parties involved in transfusion medicine, including national haemovigilance systems, is crucial for protecting a secure blood product supply from known and emerging blood-borne pathogens.
尽管如今输血传播感染的风险比以往任何时候都低,但安全血液制品的供应仍可能受到已知和尚未识别的人类病原体的污染。只有不断改进并实施献血者选择、灵敏的筛查检测和有效的灭活程序,才能确保消除或至少降低感染输血传播感染的风险。此外,持续开展教育并提供有关可能通过血液成分传播的感染源的最新信息,对于促进不良事件报告至关重要,而不良事件报告是输血传播疾病监测的一个重要组成部分。因此,包括国家血液警戒系统在内的输血医学所有相关方的合作,对于保护安全的血液制品供应免受已知和新出现的血源性病原体的侵害至关重要。