Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Cad Saude Publica. 2011 Apr;27(4):753-8. doi: 10.1590/s0102-311x2011000400014.
This study was carried out to determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) markers among adolescents aged between 10 and 16 years old, who are elementary school students in the city of Chapecó, Santa Catarina State, Brazil. The study involved a cross-sectional survey that included 418 volunteers, from March to July, 2008. Serology comprised HBsAg, anti-HBc, anti-HBs and anti-HCV. Tests were performed using automated Microparticle Enzyme Immunosorbant Assay (Abbott, AxSYM System, Wiesbaden, Germany). The prevalence of HBsAg was found to be 0.2% (95%CI: 0.0-1.3), and the prevalence of anti-HBc was found to be 1.4% (95%CI: 0.5-3.1). Regarding anti-HBs, 48.6% had titers greater than 10UI/L. None of the volunteers presented reactive results for anti-HCV. This study showed a low prevalence of HBV and HCV markers of infection and a great number of volunteers immunized against HBV. Finally this study shows the importance of proper health campaigns and policies in reducing those prevalences.
本研究旨在确定巴西圣卡塔琳娜州沙佩科市年龄在 10 至 16 岁之间的小学生中乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）标志物的流行情况。该研究采用了横断面调查，于 2008 年 3 月至 7 月间纳入了 418 名志愿者。血清学检测包括 HBsAg、抗-HBc、抗-HBs 和抗-HCV。检测使用自动化微粒子酶免疫吸附测定法（Abbott，AxSYM 系统，德国威斯巴登）进行。HBsAg 的流行率为 0.2%（95%CI：0.0-1.3），抗-HBc 的流行率为 1.4%（95%CI：0.5-3.1）。关于抗-HBs，48.6%的志愿者的滴度大于 10UI/L。没有志愿者的抗-HCV 检测结果呈阳性。本研究显示 HBV 和 HCV 感染标志物的流行率较低，且大量志愿者对 HBV 具有免疫力。最后，本研究表明，适当的健康宣传和政策对于降低这些流行率非常重要。
