Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Br J Radiol. 2011 Jun;84(1002):534-45. doi: 10.1259/bjr/72327299.
Quality assurance data from five centres were analysed to assess the reliability of RapidArc radiotherapy delivery in terms of machine and dosimetric performance.
A large group of patients was treated with RapidArc radiotherapy and treatment data recorded. Machine quality assurance was performed according to Ling et al (Int J Radiat Oncol Biol Phys 2008;72:575-81). In addition, treatment to a typical clinical case was delivered biweekly as a constancy check. Pre-treatment dosimetric validation of plan delivery was performed for each patient. All measurements and computations were performed at the depth of the maximum dose in water according to the GLAaS method using electronic portal imaging device measurements. Evaluation was carried out according to a gamma agreement index (GAI, the percentage of field area passing the test); the threshold dose difference was 3% and the threshold distance to agreement was 3 mm.
A total of 275 patients (395 arcs) were included in the study. Mean delivery parameters were 31.0±20.0° (collimator angle), 4.7±0.5° s(-1) (gantry speed), 343±134 MU min(-1) (dose rate) and 1.6±1.4 min (beam-on time) for prescription doses ranging from 1.8 to 16.7 Gy/fraction. Mean deviations from the baseline dose rate and gantry speed ranged from -0.61% to 1.75%. Mean deviations from the baseline for leaf speed variation ranged from -0.73% to 0.41%. The mean GAI of repeated clinical fields was 99.2±0.2%. GAI varied from 84.7% to 100%; the mean across all patients was 97.1±2.4%.
RapidArc can provide a reliable and accurate delivery of radiotherapy for a variety of clinical conditions.
分析来自五个中心的质量保证数据,以评估 RapidArc 放射治疗在机器和剂量学性能方面的可靠性。
对大量患者进行 RapidArc 放射治疗,并记录治疗数据。根据 Ling 等人的方法(Int J Radiat Oncol Biol Phys 2008;72:575-81)进行机器质量保证。此外,每周两次进行典型临床病例的治疗,作为恒定性检查。对每位患者的计划交付进行治疗前剂量验证。所有测量和计算均根据 GLAaS 方法在水的最大剂量深度进行,使用电子门户成像设备测量。根据伽马一致性指数(GAI,通过测试的场面积百分比)进行评估;阈值剂量差为 3%,阈值符合距离为 3mm。
共有 275 名患者(395 个弧)纳入研究。处方剂量范围为 1.8 至 16.7Gy/分次时,平均输送参数为 31.0±20.0°(准直器角度)、4.7±0.5°s(-1)(转台速度)、343±134MU min(-1)(剂量率)和 1.6±1.4 min(束流时间)。剂量率和转台速度的平均偏差范围为-0.61%至 1.75%。叶片速度变化的平均偏差范围为-0.73%至 0.41%。重复临床场的平均 GAI 为 99.2±0.2%。GAI 变化范围为 84.7%至 100%;所有患者的平均 GAI 为 97.1±2.4%。
RapidArc 可为各种临床情况提供可靠、准确的放射治疗。