Barnes Michael P, Greer Peter B
Calvary Mater Hospital; University of Newcastle.
J Appl Clin Med Phys. 2016 Mar 8;17(2):220-230. doi: 10.1120/jacmp.v17i2.6026.
In volumetric-modulated arc therapy (VMAT) treatment delivery perfect beam symmetry is assumed by the planning system. This study aims to test this assumption and present a method of measuring time-resolved beam symmetry measurement during a VMAT delivery that includes extreme variations of dose rate and gantry speed. The Sun Nuclear IC Profiler in gantry mount was used to measure time-resolved in-plane and cross-plane profiles during plan delivery from which symmetry could be determined. Time-resolved symmetry measurements were performed throughout static field exposures at cardinal gantry angles, conformal arcs with constant dose rate and gantry speed, and during a VMAT test plan with gantry speed and dose rate modulation. Measurements were performed for both clockwise and counterclockwise gantry rotation and across four Varian 21iX lin-acs. The symmetry was found to be generally constant throughout the static field exposures to within 0.3% with an exception on one linac of up to 0.7%. Agreement in symmetry between cardinal angles was always within 1.0% and typically within 0.6%. During conformal arcs the results for clockwise and counterclockwise rotation were in agreement to within 0.3%. Both clockwise and counterclockwise tended to vary in similar manner by up to 0.5% during arc consistent with the cardinal gantry angle static field results. During the VMAT test plan the symmetry generally was in agreement with the conformal arc results. Greater variation in symmetry was observed in the low-dose-rate regions by up to 1.75%. All results were within clinically acceptable levels using the tolerances of NCS Report 24 (2015).
在容积调强弧形治疗(VMAT)中,计划系统假定射束具有完美的对称性。本研究旨在验证这一假设,并提出一种在VMAT治疗过程中测量时间分辨射束对称性的方法,该方法涵盖了剂量率和机架速度的极端变化。使用安装在机架上的Sun Nuclear IC Profiler在计划执行过程中测量时间分辨的平面内和平面交叉轮廓,由此可确定对称性。在基本机架角度的静态野照射、恒定剂量率和机架速度的适形弧以及带有机架速度和剂量率调制的VMAT测试计划期间,均进行了时间分辨对称性测量。对顺时针和逆时针机架旋转以及四台Varian 21iX直线加速器均进行了测量。结果发现,在静态野照射期间,对称性总体上保持恒定,偏差在0.3%以内,但有一台直线加速器的偏差高达0.7%。基本角度之间的对称性一致性始终在1.0%以内,通常在0.6%以内。在适形弧期间,顺时针和逆时针旋转的结果一致性在0.3%以内。在弧形期间,顺时针和逆时针方向的变化趋势相似,偏差高达0.5%,这与基本机架角度静态野的结果一致。在VMAT测试计划期间,对称性总体上与适形弧的结果一致。在低剂量率区域观察到对称性有更大的变化,高达1.75%。使用NCS报告24(2015)的公差标准,所有结果均在临床可接受水平内。