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本文引用的文献

1
A molecular dynamics simulation study on trapping ions in a nanoscale Paul trap.关于在纳米级保罗阱中捕获离子的分子动力学模拟研究。
Nanotechnology. 2008 May 14;19(19):195702. doi: 10.1088/0957-4484/19/19/195702. Epub 2008 Apr 8.
2
Ultrahigh-mass mass spectrometry of single biomolecules and bioparticles.单生物分子和生物颗粒的超高质量质谱分析。
Annu Rev Anal Chem (Palo Alto Calif). 2009;2:169-85. doi: 10.1146/annurev-anchem-060908-155245.
3
Watching conformational- and photo-dynamics of single fluorescent proteins in solution.在溶液中观察单荧光蛋白的构象和光动力学。
Nat Chem. 2010 Mar;2(3):179-86. doi: 10.1038/nchem.545.
4
A long DNA segment in a linear nanoscale Paul trap.线性纳米级保罗阱中的长 DNA 片段。
Nanotechnology. 2010 Jan 8;21(1):015103. doi: 10.1088/0957-4484/21/1/015103. Epub 2009 Nov 30.
5
The potential and challenges of nanopore sequencing.纳米孔测序的潜力与挑战。
Nat Biotechnol. 2008 Oct;26(10):1146-53. doi: 10.1038/nbt.1495.
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Design, microfabrication, and analysis of micrometer-sized cylindrical ion trap arrays.微米级圆柱形离子阱阵列的设计、微加工与分析。
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7
Nanoscale paul trapping of a single electron.单个电子的纳米级保罗阱捕获
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8
Electrical forces for microscale cell manipulation.用于微尺度细胞操控的电力。
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Trapping single molecules by dielectrophoresis.通过介电泳捕获单个分子。
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10
Massively parallel manipulation of single cells and microparticles using optical images.利用光学图像对单细胞和微粒进行大规模并行操作。
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保罗在水溶液中捕获带电粒子。

Paul trapping of charged particles in aqueous solution.

机构信息

Department of Electrical Engineering, Yale University, New Haven, CT 06520, USA.

出版信息

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9326-30. doi: 10.1073/pnas.1100977108. Epub 2011 May 23.

DOI:10.1073/pnas.1100977108
PMID:21606331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3111334/
Abstract

We experimentally demonstrate the feasibility of an aqueous Paul trap using a proof-of-principle planar device. Radio frequency voltages are used to generate an alternating focusing/defocusing potential well in two orthogonal directions. Individual charged particles are dynamically confined into nanometer scale in space. Compared with conventional Paul traps working in frictionless vacuum, the aqueous environment associated with damping forces and thermally induced fluctuations (Brownian noise) exerts a fundamental influence on the underlying physics. We investigate the impact of these two effects on the confining dynamics, with the aim to reduce the rms value of the positional fluctuations. We find that the rms fluctuations can be modulated by adjusting the voltages and frequencies. This technique provides an alternative for the localization and control of charged particles in an aqueous environment.

摘要

我们通过一个原理验证的平面设备,实验证明了用水做的 Paul 阱的可行性。射频电压用于在两个正交方向上产生交替的聚焦/散焦势阱。单个带电粒子在纳米尺度的空间中被动态约束。与在无摩擦真空环境中工作的传统 Paul 阱相比,与阻尼力和热诱导波动(布朗噪声)相关的水介质环境对基础物理产生了根本影响。我们研究了这两种效应对约束动力学的影响,目的是降低位置波动的均方根值。我们发现通过调整电压和频率可以调制均方根波动。这项技术为在水介质环境中定位和控制带电粒子提供了一种替代方法。