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科索沃孕妇的弓形虫病

Toxoplasmosis in Kosovo pregnant women.

作者信息

Dentico Pietro, Volpe Anna, Putoto Giovanni, Ramadani Naser, Bertinato Luigi, Berisha Merita, Schinaia Nicola, Quaglio Gianluca, Maggi Paolo

机构信息

Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari, Bari, Italy.

出版信息

New Microbiol. 2011 Apr;34(2):203-7. Epub 2011 Apr 30.

Abstract

This study presents the initial results of a collaborative project aimed at the evaluation of Toxoplasma seroprevalence in a population of Kosovar pregnant women. The serum samples of 334 pregnant women were tested to detect IgG, IgM, IgG avidity for toxoplasmosis. Data regarding age, occupation, area of origin and education were also obtained for the pregnant women examined; 97/334 (29.4%) resulted positive for IgG antibodies, four of whom (4.1%) were also positive for IgM, (1.2% of the total population examined). All four IgM-positive pregnant women also demonstrated low avidity tests. The rate of IgG seroprevalence found in our study was lower than that observed in various European countries, especially those of western Europe. Conversely, the percentage of recent infections was higher than expected. The higher rate of infections could be the result of a recent toxoplasmosis epidemic in Kosovo, most likely due to the altered hygienic conditions caused by the forced transfer of the ethnic-Albanian population from an area of low (Serbia) to high (Kosovo) toxoplasmosis prevalence.

摘要

本研究展示了一个合作项目的初步结果,该项目旨在评估科索沃孕妇群体中的弓形虫血清阳性率。对334名孕妇的血清样本进行检测,以检测弓形虫病的IgG、IgM和IgG亲和力。还获取了接受检查的孕妇的年龄、职业、原籍地区和教育程度等数据;97/334(29.4%)的孕妇IgG抗体检测呈阳性,其中4人(4.1%)IgM也呈阳性(占总检查人群的1.2%)。所有4名IgM阳性孕妇的亲和力检测结果也都较低。我们研究中发现的IgG血清阳性率低于在欧洲各国尤其是西欧各国观察到的水平。相反,近期感染的百分比高于预期。感染率较高可能是科索沃近期弓形虫病流行的结果,很可能是由于阿尔巴尼亚族人口从弓形虫病患病率低的地区(塞尔维亚)被迫转移到患病率高的地区(科索沃)导致卫生条件改变所致。

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