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骨关节炎滑液中的白三烯B4和前列腺素E2样活性

Leukotriene B4 and prostaglandin E2-like activity in synovial fluid in osteoarthritis.

作者信息

Sahap Atik O

机构信息

Gaza University Medical Faculty, Sölen Sok. Basintepe C/6, Ankara, Turkey.

出版信息

Prostaglandins Leukot Essent Fatty Acids. 1990 Apr;39(4):253-4. doi: 10.1016/0952-3278(90)90002-3.

DOI:10.1016/0952-3278(90)90002-3
PMID:2162064
Abstract

LTB4 and PGE2-like activity in synovial fluid samples from patients with osteoarthritis of the knee joint were determined and found to be significantly higher than in samples obtained from normal patients. The results suggest that leukotrienes and prostaglandins may have a role in the pathogenesis of osteoarthritis.

摘要

对膝关节骨关节炎患者滑液样本中的白三烯B4（LTB4）和类前列腺素E2（PGE2）活性进行了测定，发现其显著高于正常患者的样本。结果表明，白三烯和前列腺素可能在骨关节炎的发病机制中起作用。

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