Bacteriophage Laboratory, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114, Wroclaw, Poland.
Folia Microbiol (Praha). 2011 May;56(3):191-200. doi: 10.1007/s12223-011-0039-8. Epub 2011 May 31.
The ability of bacteriophages to survive under unfavorable conditions is highly diversified. We summarize the influence of different external physical and chemical factors, such as temperature, acidity, and ions, on phage persistence. The relationships between a phage's morphology and its survival abilities suggested by some authors are also discussed. A better understanding of the complex problem of phage sensitivity to external factors may be useful not only for those interested in pharmaceutical and agricultural applications of bacteriophages, but also for others working with phages.
噬菌体在不利条件下生存的能力具有高度多样性。我们总结了不同外部物理和化学因素(如温度、酸度和离子)对噬菌体持久性的影响。还讨论了一些作者提出的噬菌体形态与其生存能力之间的关系。更好地了解噬菌体对外界因素的敏感性这一复杂问题,不仅对那些对噬菌体在制药和农业方面应用感兴趣的人有用,对那些与噬菌体一起工作的人也有用。