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200 例患者中减少术后并发症的肺切除术选择。

Selection of pulmonary resection procedures to reduce postoperative complications in 200 patients.

机构信息

Department of Surgery, National Hospital Organization Omuta National Hospital, 1044-1 Tachibana, Omuta, Fukuoka, 837-0911, Japan.

出版信息

Surg Today. 2011 Jun;41(6):780-6. doi: 10.1007/s00595-010-4350-9. Epub 2011 May 28.

Abstract

PURPOSE

We previously demonstrated in a pilot study that postoperative cardiopulmonary complications could be reduced by selecting pulmonary resection procedures based on the results of a combination of specific preoperative cardiopulmonary function tests. The present study reports a re-examination of the criteria for preoperative screening and prospectively assessed whether the selected surgical procedures were appropriate in 200 patients who underwent the planned extent of pulmonary resection.

METHODS

In 200 patients requiring lung tumor resection, five preoperative parameters (forced expiratory volume in 1 s on the intact side, maximal oxygen uptake, ejection fraction, occluded pulmonary artery pressure, and occluded total pulmonary vascular resistance index) were used to assign each patient to one of five risk categories in order to select the optimal resection procedure. Thereafter, the postoperative course was investigated to determine the value of this selection method.

RESULTS

Thoracotomy was performed in 195 of the 200 patients (97.5%). Two patients (1%) died; one patient succumbed to acute exacerbation of interstitial pneumonia and the other patient died from pulmonary embolism. Six patients (3.1%) developed major complications after surgery and 12 patients (6.2%) had mild complications, while 175 (89.7%) showed a good postoperative course.

CONCLUSION

The use of five preoperative parameters to select the pulmonary resection procedure minimized postoperative death and major complications.

摘要

目的

我们之前的一项初步研究表明,通过结合特定的术前心肺功能测试结果选择肺切除术式,可以降低术后心肺并发症的发生率。本研究再次检验了术前筛查的标准,并前瞻性评估了在 200 例计划行肺切除术的患者中,选择的手术方式是否合适。

方法

在 200 例需要进行肺肿瘤切除术的患者中,使用 5 项术前参数(健侧 1 秒用力呼气容积、最大摄氧量、射血分数、肺动脉阻塞压和总肺血管阻力指数)将每位患者分配到 5 个风险类别中的一个,以选择最佳的切除程序。然后,对术后过程进行了调查,以确定这种选择方法的价值。

结果

200 例患者中有 195 例(97.5%)进行了开胸手术。2 例(1%)患者死亡;1 例死于间质性肺炎急性加重,另 1 例死于肺栓塞。6 例(3.1%)患者术后发生严重并发症,12 例(6.2%)患者发生轻度并发症,175 例(89.7%)患者术后情况良好。

结论

使用 5 项术前参数选择肺切除术式可最大限度地降低术后死亡率和严重并发症的发生。

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