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经皮治疗椎间盘突出症。

Percutaneous treatment of intervertebral disc herniation.

作者信息

Buy Xavier, Gangi Afshin

机构信息

Department of Radiology B, University Hospital of Strasbourg, Strasbourg, France.

出版信息

Semin Intervent Radiol. 2010 Jun;27(2):148-59. doi: 10.1055/s-0030-1253513.

Abstract

Interventional radiology plays a major role in the management of symptomatic intervertebral disc herniations. In the absence of significant pain relief with conservative treatment including oral pain killers and anti-inflammatory drugs, selective image-guided periradicular infiltrations are generally indicated. The precise control of needle positioning allows optimal distribution of steroids along the painful nerve root. After 6 weeks of failure of conservative treatment including periradicular infiltration, treatment aiming to decompress or remove the herniation is considered. Conventional open surgery offers suboptimal results and is associated with significant morbidity. To achieve minimally invasive discal decompression, different percutaneous techniques have been developed. Their principle is to remove a small volume of nucleus, which results in an important reduction of intradiscal pressure and subsequently reduction of pressure inside the disc herniation. However, only contained disc herniations determined by computed tomography or magnetic resonance are indicated for these techniques. Thermal techniques such as radiofrequency or laser nucleotomy seem to be more effective than purely mechanical nucleotomy; indeed, they achieve discal decompression but also thermal destruction of intradiscal nociceptors, which may play a major role in the physiopathology of discal pain. The techniques of image-guided spinal periradicular infiltration and percutaneous nucleotomy with laser and radiofrequency are presented with emphasis on their best indications.

摘要

介入放射学在有症状的椎间盘突出症的治疗中发挥着重要作用。在包括口服止痛药和抗炎药在内的保守治疗未能显著缓解疼痛的情况下,通常需要进行选择性影像引导下的神经根周围浸润。精确控制针的定位可使类固醇沿疼痛神经根实现最佳分布。在包括神经根周围浸润在内的保守治疗失败6周后,考虑进行旨在减压或切除突出物的治疗。传统的开放手术效果欠佳,且并发症发生率较高。为实现微创椎间盘减压,已开发出不同的经皮技术。其原理是去除少量髓核,这会导致椎间盘内压力显著降低,进而使椎间盘突出物内部压力降低。然而,这些技术仅适用于由计算机断层扫描或磁共振成像确定的包容性椎间盘突出。射频或激光髓核切除术等热技术似乎比单纯的机械髓核切除术更有效;实际上,它们不仅能实现椎间盘减压,还能对椎间盘内的伤害感受器进行热破坏,而伤害感受器可能在椎间盘疼痛的病理生理过程中起主要作用。本文重点介绍了影像引导下的脊柱神经根周围浸润以及激光和射频经皮髓核切除术的技术及其最佳适应证。

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