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在大鼠脑发育过程中，少突胶质细胞中H1(0)和A24的相对比例发生了逆转。

The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development.

作者信息

Di Liegro I, Cestelli A

机构信息

Dipartimento di Biologia Cellulare e dello Sviluppo, Università degli Studi, Palermo, Italy.

出版信息

Cell Mol Neurobiol. 1990 Jun;10(2):267-74. doi: 10.1007/BF00734579.

DOI:10.1007/BF00734579
PMID:2163755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11567209/
Abstract
  1. The histone complement of oligodendrocyte chromatin at different stages of brain development was studied after acid extraction of nuclei. 2. HCl-soluble proteins were analyzed by different electrophoretic techniques. 3. Our results show an increase in the concentration of histone H1(0) with differentiation. 4. The increase in H1(0) is accompanied by a concomitant decrease in the total amount of the ubiquitinated form of histone H2A (A24).
摘要
  1. 在对细胞核进行酸提取后，研究了脑发育不同阶段少突胶质细胞染色质的组蛋白组成。2. 采用不同的电泳技术分析了盐酸可溶性蛋白。3. 我们的结果表明，随着分化，组蛋白H1(0)的浓度增加。4. H1(0)的增加伴随着组蛋白H2A泛素化形式（A24）总量的相应减少。

相似文献

1
The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development.在大鼠脑发育过程中，少突胶质细胞中H1(0)和A24的相对比例发生了逆转。
Cell Mol Neurobiol. 1990 Jun;10(2):267-74. doi: 10.1007/BF00734579.
2
Histone H1o in developing rat brain cells.发育中大鼠脑细胞中的组蛋白H1o
Differentiation. 1984;28(2):191-4. doi: 10.1111/j.1432-0436.1984.tb00283.x.
3
Qualitative differences in nuclear proteins correlate with neuronal terminal differentiation.核蛋白的定性差异与神经元终末分化相关。
Cell Mol Neurobiol. 1992 Feb;12(1):33-43. doi: 10.1007/BF00711637.
4
Histone 1 is proximal to histone 2A and to A24.组蛋白1靠近组蛋白2A和A24。
Proc Natl Acad Sci U S A. 1979 May;76(5):2190-4. doi: 10.1073/pnas.76.5.2190.
5
The ubiquitinated histone species are enriched in histone H1-depleted chromatin regions.泛素化的组蛋白种类在缺乏组蛋白H1的染色质区域中富集。
Biochim Biophys Acta. 1987 Aug 25;909(3):183-9. doi: 10.1016/0167-4781(87)90076-5.
6
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain.组蛋白修饰影响发育中大鼠大脑少突胶质细胞祖细胞分化的时间。
J Cell Biol. 2005 May 23;169(4):577-89. doi: 10.1083/jcb.200412101. Epub 2005 May 16.
7
Comparisons of histones in retinal and brain nuclei from newborn and adult mice.新生和成年小鼠视网膜与脑细胞核中组蛋白的比较。
Brain Res. 1987 Jun;430(2):161-8. doi: 10.1016/0165-3806(87)90150-7.
8
Age-dependent deamidation of H1(0) histones in chromatin of mammalian tissues.哺乳动物组织染色质中H1(0)组蛋白的年龄依赖性脱酰胺作用。
J Cancer Res Clin Oncol. 1999;125(3-4):182-6. doi: 10.1007/s004320050261.
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Chromatin conjugate protein A24 is cleaved and ubiquitin is lost during chicken erythropoiesis.在鸡红细胞生成过程中，染色质结合蛋白A24被切割，泛素丢失。
J Biol Chem. 1980 Nov 25;255(22):10555-8.
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Changes in nuclear content of protein conjugate histone H2A-ubiquitin during rooster spermatogenesis.公鸡精子发生过程中蛋白质结合物组蛋白H2A-泛素的核含量变化。
FEBS Lett. 1983 May 8;155(2):209-12. doi: 10.1016/0014-5793(82)80604-2.

引用本文的文献

1
H1.0 Linker Histone as an Epigenetic Regulator of Cell Proliferation and Differentiation.H1.0连接组蛋白作为细胞增殖和分化的表观遗传调节因子
Genes (Basel). 2018 Jun 20;9(6):310. doi: 10.3390/genes9060310.
2
Effects of triiodothyronine (T3) on differentiation of rat cortical neurons in primary cultures.三碘甲状腺原氨酸（T3）对原代培养大鼠皮质神经元分化的影响。
Cytotechnology. 1991 Feb;5(Suppl 1):168-71. doi: 10.1007/BF00736840.
3
Defining the chromatin landscape in demyelinating disorders.定义脱髓鞘疾病中的染色质景观。
Neurobiol Dis. 2010 Jul;39(1):47-52. doi: 10.1016/j.nbd.2009.10.014. Epub 2009 Oct 22.
4
H1(0) and H3.3B mRNA levels in developing rat brain.发育中大鼠大脑中H1(0)和H3.3B的mRNA水平。
Neurochem Res. 1994 Dec;19(12):1531-7. doi: 10.1007/BF00969002.
5
Qualitative differences in nuclear proteins correlate with neuronal terminal differentiation.核蛋白的定性差异与神经元终末分化相关。
Cell Mol Neurobiol. 1992 Feb;12(1):33-43. doi: 10.1007/BF00711637.
6
The dynamic properties of neuronal chromatin are modulated by triiodothyronine.神经元染色质的动态特性受三碘甲状腺原氨酸调控。
Neurochem Res. 1992 Nov;17(11):1049-55. doi: 10.1007/BF00967280.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Orientation of the nucleosome within the higher order structure of chromatin.核小体在染色质高级结构中的定位。
Cell. 1980 Nov;22(1 Pt 1):87-96. doi: 10.1016/0092-8674(80)90157-9.
3
Histone H10 accumulates in growth-inhibited cultured cells.组蛋白H10在生长受抑制的培养细胞中积累。
Nature. 1980 May 1;285(5759):43-4. doi: 10.1038/285043a0.
4
Chromatin organization in the rat hypothalamus during early development.大鼠下丘脑早期发育过程中的染色质组织
Biochem J. 1981 Apr 15;196(1):115-9. doi: 10.1042/bj1960115.
5
H1 histone variants in Xenopus laevis.非洲爪蟾中的H1组蛋白变体。
Dev Biol. 1981 May;84(1):79-87. doi: 10.1016/0012-1606(81)90372-9.
6
The chromatin repeat length of brain cortex and cerebellar neurons changes concomitant with terminal differentiation.大脑皮层和小脑神经元的染色质重复长度随着终末分化而变化。
EMBO J. 1982;1(7):811-6. doi: 10.1002/j.1460-2075.1982.tb01252.x.
7
Histone H1 subfractions and H10 turnover at different rates in nondividing cells.组蛋白H1亚组分和H10在非分裂细胞中的更新速率不同。
Biochemistry. 1982 Feb 2;21(3):456-60. doi: 10.1021/bi00532a006.
8
Developmental and hormonal regulation of protein H1 degrees in rodents.啮齿动物中蛋白质H1度的发育和激素调节。
Proc Natl Acad Sci U S A. 1982 Apr;79(7):2333-7. doi: 10.1073/pnas.79.7.2333.
9
Differential kinetics of histone H1(0) accumulation in neuronal and glial cells from rat cerebral cortex during postnatal development.出生后发育期间大鼠大脑皮质神经元和神经胶质细胞中组蛋白H1(0)积累的差异动力学。
Biochem Biophys Res Commun. 1984 Sep 17;123(2):697-702. doi: 10.1016/0006-291x(84)90285-7.
10
A minireview of microheterogeneity in H1 histone and its possible significance.H1组蛋白的微异质性及其潜在意义的简要综述。
Anal Biochem. 1984 Jan;136(1):24-30. doi: 10.1016/0003-2697(84)90303-8.