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在大鼠脑发育过程中,少突胶质细胞中H1(0)和A24的相对比例发生了逆转。

The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development.

作者信息

Di Liegro I, Cestelli A

机构信息

Dipartimento di Biologia Cellulare e dello Sviluppo, Università degli Studi, Palermo, Italy.

出版信息

Cell Mol Neurobiol. 1990 Jun;10(2):267-74. doi: 10.1007/BF00734579.

Abstract
  1. The histone complement of oligodendrocyte chromatin at different stages of brain development was studied after acid extraction of nuclei. 2. HCl-soluble proteins were analyzed by different electrophoretic techniques. 3. Our results show an increase in the concentration of histone H1(0) with differentiation. 4. The increase in H1(0) is accompanied by a concomitant decrease in the total amount of the ubiquitinated form of histone H2A (A24).
摘要
  1. 在对细胞核进行酸提取后,研究了脑发育不同阶段少突胶质细胞染色质的组蛋白组成。2. 采用不同的电泳技术分析了盐酸可溶性蛋白。3. 我们的结果表明,随着分化,组蛋白H1(0)的浓度增加。4. H1(0)的增加伴随着组蛋白H2A泛素化形式(A24)总量的相应减少。

相似文献

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Histone H1o in developing rat brain cells.发育中大鼠脑细胞中的组蛋白H1o
Differentiation. 1984;28(2):191-4. doi: 10.1111/j.1432-0436.1984.tb00283.x.
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Histone 1 is proximal to histone 2A and to A24.组蛋白1靠近组蛋白2A和A24。
Proc Natl Acad Sci U S A. 1979 May;76(5):2190-4. doi: 10.1073/pnas.76.5.2190.

本文引用的文献

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H1 histone variants in Xenopus laevis.非洲爪蟾中的H1组蛋白变体。
Dev Biol. 1981 May;84(1):79-87. doi: 10.1016/0012-1606(81)90372-9.

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