Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Annu Rev Biomed Eng. 2011 Aug 15;13:429-50. doi: 10.1146/annurev-bioeng-071910-124644.
Biomolecular motors, in particular motor proteins from the kinesin and myosin families, can be used to explore engineering applications of molecular motors in general. Their outstanding performance enables the experimental study of hybrid systems, where bio-inspired functions such as sensing, actuation, and transport rely on the nanoscale generation of mechanical force. Scaling laws and theoretical studies demonstrate the optimality of biomolecular motor designs and inform the development of synthetic molecular motors.
生物分子马达，特别是来自驱动蛋白和肌球蛋白家族的马达蛋白，可以用于探索分子马达在一般工程应用中的潜力。它们卓越的性能使混合系统的实验研究成为可能，其中生物启发功能，如传感、致动和运输，依赖于机械力的纳米级产生。尺度定律和理论研究证明了生物分子马达设计的最优性，并为合成分子马达的发展提供了信息。
