Jover Ana, Corbella Emili, Muñoz Anna, Millán Jesús, Pintó Xavier, Mangas Alipio, Zúñiga Manuel, Pedro-Botet Juan, Hernández-Mijares Antonio
Servicio de Endocrinología, Hospital Universitario Dr. Peset y Fundación para la Investigación Hospital Universitario Dr. Peset, Valencia, Spain.
Rev Esp Cardiol. 2011 Jul;64(7):579-86. doi: 10.1016/j.recesp.2011.03.010. Epub 2011 Jun 2.
A large proportion of patients with coronary disease have metabolic syndrome, although the frequency and association of its different components are not well understood. The aim of this study was to determine the prevalence of metabolic syndrome and the combination of its components in a Spanish cohort of patients with acute coronary syndrome.
Clinical histories of 574 inpatients with acute coronary syndrome in 6 tertiary hospitals were reviewed and the presence of metabolic syndrome and its components determined by applying Adult Treatment Panel III criteria. In a second step, the components of the metabolic syndrome were analyzed, excluding those patients with diabetes mellitus.
The metabolic syndrome was present in 50.9% of patients and was more frequent in women than in men (66.3% vs. 47.3%; P<.001). The most prevalent component was carbohydrate metabolism disorder (85.3%), followed by low high-density lipoprotein cholesterol (HDLc) levels (80.5%). In nondiabetic patients, 34.6% had metabolic syndrome and the most prevalent component was low HDLc levels (86%), followed by high blood pressure and hypertriglyceridemia and, in fourth place, impaired fasting serum glucose levels.
The metabolic syndrome has a high prevalence in patients with an acute coronary syndrome, especially in women. The most frequent components are hyperglycemia and low HDLc levels. After excluding diabetic patients, the most prevalent diagnostic criterion of metabolic syndrome was low HDLc levels. Full English text available from: www.revespcardiol.org.
很大一部分冠心病患者患有代谢综合征，但其不同组分的发生率及相关性尚未完全明确。本研究旨在确定西班牙急性冠脉综合征患者队列中代谢综合征的患病率及其组分组合情况。
回顾了6家三级医院574例急性冠脉综合征住院患者的临床病历，并应用成人治疗小组第三次报告标准确定代谢综合征及其组分的存在情况。第二步，分析代谢综合征的组分，排除糖尿病患者。
50.9%的患者存在代谢综合征，女性比男性更常见（66.3%对47.3%；P<0.001）。最常见的组分是碳水化合物代谢紊乱（85.3%），其次是高密度脂蛋白胆固醇（HDLc）水平低（80.5%）。在非糖尿病患者中，34.6%患有代谢综合征，最常见的组分是HDLc水平低（86%），其次是高血压和高甘油三酯血症，排在第四位的是空腹血清葡萄糖水平受损。
代谢综合征在急性冠脉综合征患者中患病率很高,尤其是在女性中。最常见的组分是高血糖和HDLc水平低。排除糖尿病患者后，代谢综合征最常见的诊断标准是HDLc水平低。可从www.revespcardiol.org获取全文。
