Epstein J B, Sherlock C, Page J L, Spinelli J, Phillips G
Division of Oral Medicine and Clinical Dentistry, Vancouver General Hospital, British Columbia, Canada.
Oral Surg Oral Med Oral Pathol. 1990 Jul;70(1):38-43. doi: 10.1016/0030-4220(90)90175-r.
Twenty-nine patients with leukemia were observed for the development of and recovery from oral herpes simplex virus (HSV) lesions. In patients with seropositive test results, lymphocyte and monocyte counts may provide a guide to predict the onset of HSV infections and to indicate when to institute acyclovir prophylaxis. When HSV developed, acyclovir was effective in preventing progression of the lesions, which did not resolve until white cell counts had recovered.
对29例白血病患者进行了观察，以了解口腔单纯疱疹病毒（HSV）病变的发生及恢复情况。在血清学检测结果呈阳性的患者中，淋巴细胞和单核细胞计数可为预测HSV感染的发作以及指示何时开始阿昔洛韦预防提供指导。当HSV感染发生时，阿昔洛韦可有效预防病变进展，病变直至白细胞计数恢复才消退。
