• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Gelsemine and Gelsemium sempervirens L. Extracts in Animal Behavioral Test: Comments and Related Biases.

作者信息

Chirumbolo Salvatore

机构信息

Department of Pathology and Diagnostics, University of Verona Verona, Italy.

出版信息

Front Neurol. 2011 May 16;2:31. doi: 10.3389/fneur.2011.00031. eCollection 2011.

DOI:10.3389/fneur.2011.00031
PMID:21647210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3098419/
Abstract
摘要

相似文献

1
Gelsemine and Gelsemium sempervirens L. Extracts in Animal Behavioral Test: Comments and Related Biases.钩吻素和常绿钩吻提取物的动物行为测试:评论及相关偏差
Front Neurol. 2011 May 16;2:31. doi: 10.3389/fneur.2011.00031. eCollection 2011.
2
Comparative Analysis of Gelsemine and Gelsemium sempervirens Activity on Neurosteroid Allopregnanolone Formation in the Spinal Cord and Limbic System.比较钩藤堿和钩藤在脊髓和边缘系统神经甾体别孕烯醇酮形成中的活性。
Evid Based Complement Alternat Med. 2011;2011:407617. doi: 10.1093/ecam/nep083. Epub 2011 Jun 16.
3
Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and specific antinociception in chronic pain by acting at spinal α3 glycine receptors.钩吻素甲,钩吻常绿藤本植物中的主要生物碱,通过作用于脊髓 α3 型甘氨酸受体对慢性疼痛表现出强效和特异的镇痛作用。
Pain. 2013 Nov;154(11):2452-2462. doi: 10.1016/j.pain.2013.07.027. Epub 2013 Jul 22.
4
Effects of Gelsemium sempervirens L. on pathway-focused gene expression profiling in neuronal cells.钩吻对神经元细胞中通路聚焦基因表达谱的影响。
J Ethnopharmacol. 2014 Apr 28;153(2):535-9. doi: 10.1016/j.jep.2014.02.048. Epub 2014 Mar 5.
5
Gelsemine and koumine, principal active ingredients of Gelsemium, exhibit mechanical antiallodynia via spinal glycine receptor activation-induced allopregnanolone biosynthesis.钩吻中的主要活性成分钩藤碱和胡蔓藤碱通过脊髓甘氨酸受体激活诱导异孕烯醇酮生物合成发挥机械性抗痛觉过敏作用。
Biochem Pharmacol. 2019 Mar;161:136-148. doi: 10.1016/j.bcp.2019.01.014. Epub 2019 Jan 19.
6
Gelsemium analgesia and the spinal glycine receptor/allopregnanolone pathway.钩吻镇痛与脊髓甘氨酸受体/别孕烯醇酮途径。
Fitoterapia. 2015 Jan;100:35-43. doi: 10.1016/j.fitote.2014.11.002. Epub 2014 Nov 11.
7
[Gelsemium, in The Big Four].
Brain Nerve. 2023 Dec;75(12):1293-1296. doi: 10.11477/mf.1416202525.
8
Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice.高稀释度钩吻对小鼠焦虑相关反应的量效研究。
Psychopharmacology (Berl). 2010 Jul;210(4):533-45. doi: 10.1007/s00213-010-1855-2. Epub 2010 Apr 20.
9
High diluted molecules and gene expression.高稀释分子与基因表达。
Front Pharmacol. 2014 Aug 14;5:183. doi: 10.3389/fphar.2014.00183. eCollection 2014.
10
Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice.钩吻素甲,一种从钩吻中提取的天然生物碱,可减轻 Aβ 寡聚体处理的小鼠的神经炎症和认知障碍。
Psychopharmacology (Berl). 2020 Jul;237(7):2111-2124. doi: 10.1007/s00213-020-05522-y. Epub 2020 May 4.

引用本文的文献

1
Bias and misleading concepts in an Arnica research study. Comments to improve experimental Homeopathy.山金车属植物研究中的偏差与误导性概念。关于改进顺势疗法实验的评论
J Ayurveda Integr Med. 2018 Jan-Mar;9(1):75-80. doi: 10.1016/j.jaim.2017.01.014. Epub 2018 Feb 26.
2
Experimental neuropharmacology of Gelsemium sempervirens: Recent advances and debated issues.钩吻的实验神经药理学:最新进展与争议问题
J Ayurveda Integr Med. 2018 Jan-Mar;9(1):69-74. doi: 10.1016/j.jaim.2017.01.010. Epub 2018 Feb 7.
3
Koumine exhibits anxiolytic properties without inducing adverse neurological effects on functional observation battery, open-field and Vogel conflict tests in rodents.钩吻素子具有抗焦虑特性,且对啮齿动物的功能观测组合、旷场试验和Vogel冲突试验均未产生不良神经学影响。
J Nat Med. 2017 Apr;71(2):397-408. doi: 10.1007/s11418-017-1070-0. Epub 2017 Jan 19.
4
Antioxidant, Antinociceptive and CNS Activities of Viscum orientale and High Sensitive Quantification of Bioactive Polyphenols by UPLC.东方槲寄生的抗氧化、抗伤害感受及中枢神经系统活性以及通过超高效液相色谱法对生物活性多酚进行高灵敏度定量分析
Front Pharmacol. 2016 Jun 29;7:176. doi: 10.3389/fphar.2016.00176. eCollection 2016.
5
On Gelsemium and Complementary and Alternative Medicine (CAM) in Anxiety and Experimental Neurology.钩吻与焦虑症和实验神经病学中的补充与替代医学
Neurol Ther. 2015 Jun;4(1):1-10. doi: 10.1007/s40120-014-0025-6. Epub 2014 Dec 19.
6
Bioactive Polyphenols from the Methanol Extract of Cnicus arvensis (L.) Roth Demonstrated Antinociceptive and Central Nervous System Depressant Activities in Mice.来自田野菊(Cnicus arvensis (L.) Roth)甲醇提取物的生物活性多酚在小鼠中表现出抗伤害感受和中枢神经系统抑制活性。
Evid Based Complement Alternat Med. 2015;2015:794729. doi: 10.1155/2015/794729. Epub 2015 Jan 14.
7
Gelsemium sempervirens and Animal Behavioral Models.钩吻与动物行为模型。
Front Neurol. 2011 Sep 12;2:56. doi: 10.3389/fneur.2011.00056. eCollection 2011.

本文引用的文献

1
Randomized blinding in basic research of homeopathy: some comments.
Complement Ther Med. 2011 Apr;19(2):107-8. doi: 10.1016/j.ctim.2010.12.010. Epub 2011 Jan 31.
2
Antianxiety activity of Gelsemium sempervirens.钩吻的抗焦虑活性。
Pharm Biol. 2010 Oct;48(10):1091-6. doi: 10.3109/13880200903490521.
3
How the number of learning trials affects placebo and nocebo responses.学习试验次数如何影响安慰剂和反安慰剂反应。
Pain. 2010 Nov;151(2):430-439. doi: 10.1016/j.pain.2010.08.007.
4
Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice.高稀释度钩吻对小鼠焦虑相关反应的量效研究。
Psychopharmacology (Berl). 2010 Jul;210(4):533-45. doi: 10.1007/s00213-010-1855-2. Epub 2010 Apr 20.
5
Biomedical research. Of mice and women: the bias in animal models.生物医学研究。论小鼠与女性:动物模型中的偏见。
Science. 2010 Mar 26;327(5973):1571-2. doi: 10.1126/science.327.5973.1571.
6
Contributions of the amygdala central nucleus and ventrolateral periaqueductal grey to freezing and instrumental suppression in Pavlovian fear conditioning.杏仁中央核和腹外侧导水管周围灰质在条件性恐惧反应中的冻结和工具性抑制的贡献。
Behav Brain Res. 2010 Jul 29;211(1):111-7. doi: 10.1016/j.bbr.2010.03.020. Epub 2010 Mar 16.
7
Animal models for studying homeopathy and high dilutions: conceptual critical review.用于研究顺势疗法和高稀释度的动物模型:概念性批判性综述。
Homeopathy. 2010 Jan;99(1):37-50. doi: 10.1016/j.homp.2009.11.003.
8
Assays of homeopathic remedies in rodent behavioural and psychopathological models.顺势疗法药物在啮齿动物行为和精神病理学模型中的检测
Homeopathy. 2009 Oct;98(4):208-27. doi: 10.1016/j.homp.2009.09.005.
9
Comparative Analysis of Gelsemine and Gelsemium sempervirens Activity on Neurosteroid Allopregnanolone Formation in the Spinal Cord and Limbic System.比较钩藤堿和钩藤在脊髓和边缘系统神经甾体别孕烯醇酮形成中的活性。
Evid Based Complement Alternat Med. 2011;2011:407617. doi: 10.1093/ecam/nep083. Epub 2011 Jun 16.
10
Confirmation of gelsemium poisoning by targeted analysis of toxic gelsemium alkaloids in urine.通过尿液中有毒钩吻生物碱的靶向分析确认钩吻中毒
J Anal Toxicol. 2009 Jan-Feb;33(1):56-61. doi: 10.1093/jat/33.1.56.