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本文引用的文献

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The detection of specific biomolecular interactions with micro-Hall magnetic sensors.利用微霍尔磁传感器检测特定生物分子相互作用。
Nanotechnology. 2009 Sep 2;20(35):355501. doi: 10.1088/0957-4484/20/35/355501. Epub 2009 Aug 12.
2
High throughput system for magnetic manipulation of cells, polymers, and biomaterials.用于细胞、聚合物和生物材料磁操控的高通量系统。
Rev Sci Instrum. 2008 Aug;79(8):083707. doi: 10.1063/1.2976156.
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Spin valve sensors for ultrasensitive detection of superparamagnetic nanoparticles for biological applications.用于生物应用中超顺磁性纳米颗粒超灵敏检测的自旋阀传感器。
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On-chip manipulation and detection of magnetic particles for functional biosensors.用于功能性生物传感器的磁性颗粒的芯片上操控与检测
Biosens Bioelectron. 2008 Jan 18;23(6):833-8. doi: 10.1016/j.bios.2007.08.023. Epub 2007 Sep 6.
5
An integrated microfluidic system using magnetic beads for virus detection.一种使用磁珠进行病毒检测的集成微流控系统。
Diagn Microbiol Infect Dis. 2008 Jan;60(1):51-8. doi: 10.1016/j.diagmicrobio.2007.07.010. Epub 2007 Oct 29.
6
Applications of microfluidics in chemical biology.微流控技术在化学生物学中的应用。
Curr Opin Chem Biol. 2006 Dec;10(6):584-91. doi: 10.1016/j.cbpa.2006.10.016. Epub 2006 Oct 23.
7
An integrated microfluidic biochemical detection system for protein analysis with magnetic bead-based sampling capabilities.一种用于蛋白质分析的集成微流控生化检测系统,具有基于磁珠的采样能力。
Lab Chip. 2002 Feb;2(1):27-30. doi: 10.1039/b107540n. Epub 2001 Dec 6.

微流控通道中超顺磁珠的动态微霍尔检测

Dynamic micro-Hall detection of superparamagnetic beads in a microfluidic channel.

作者信息

Aledealat K, Mihajlović G, Chen K, Field M, Sullivan G J, Xiong P, Chase P B, von Molnár S

机构信息

Department of Physics and MARTECH, Florida State University, Tallahassee, FL 32306, United States.

出版信息

J Magn Magn Mater. 2010 Dec 1;322(24):L69-L72. doi: 10.1016/j.jmmm.2010.08.006.

DOI:10.1016/j.jmmm.2010.08.006
PMID:21655331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3108004/
Abstract

We report integration of an InAs quantum well micro-Hall magnetic sensor with microfluidics and real-time detection of moving superparamagnetic beads. Beads moving within and around the Hall cross area result in positive and negative Hall voltage signals respectively. Relative magnitudes and polarities of the signals measured for a random distribution of immobilized beads over the sensor are in good agreement with calculated values and explain consistently the shape of the dynamic signal.

摘要

我们报告了将一个砷化铟量子阱微霍尔磁传感器与微流体技术集成,并对移动的超顺磁珠进行实时检测。在霍尔交叉区域内和周围移动的珠子分别导致正霍尔电压信号和负霍尔电压信号。对于固定在传感器上的珠子随机分布所测量的信号的相对大小和极性与计算值高度吻合,并一致地解释了动态信号的形状。