Wu Kai, Liu Jinming, Saha Renata, Peng Chaoyi, Su Diqing, Wang Yongqiang Andrew, Wang Jian-Ping
Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Department of Chemical Engineering and Material Science, University of Minnesota, Minneapolis, Minnesota 55455, United States.
ACS Omega. 2021 Feb 26;6(9):6274-6283. doi: 10.1021/acsomega.0c05845. eCollection 2021 Mar 9.
Magnetic nanoparticles (MNPs) have been extensively used as tiny heating sources in magnetic hyperthermia therapy, contrast agents in magnetic resonance imaging, tracers in magnetic particle imaging, carriers for drug/gene delivery, etc. There have emerged many MNP/microbead suppliers since the past decade, such as Ocean NanoTech, Nanoprobes, US Research Nanomaterials, Miltenyi Biotec, micromod Partikeltechnologie GmbH, nanoComposix, and so forth. In this paper, we report the physical and magnetic characterizations on iron oxide nanoparticle products from Ocean NanoTech. Standard characterization tools such as vibrating-sample magnetometry, X-ray diffraction, dynamic light scattering, transmission electron microscopy, and zeta potential analysis are used to provide MNP customers and researchers with an overview of these iron oxide nanoparticle products. In addition, the dynamic magnetic responses of these iron oxide nanoparticles in aqueous solutions are investigated under low- and high-frequency alternating magnetic fields, giving a standardized operating procedure for characterizing the MNPs from Ocean NanoTech, thereby yielding the best of MNPs for different applications.
磁性纳米粒子(MNPs)已被广泛用作磁热疗中的微小热源、磁共振成像中的造影剂、磁粒子成像中的示踪剂、药物/基因递送载体等。自过去十年以来,出现了许多磁性纳米粒子/微珠供应商,如海洋纳米技术公司(Ocean NanoTech)、纳米探针公司(Nanoprobes)、美国研究纳米材料公司(US Research Nanomaterials)、美天旎生物技术公司(Miltenyi Biotec)、微模颗粒技术有限公司(micromod Partikeltechnologie GmbH)、纳米复合材料公司(nanoComposix)等等。在本文中,我们报告了对海洋纳米技术公司生产的氧化铁纳米粒子产品的物理和磁性表征。使用诸如振动样品磁强计、X射线衍射、动态光散射、透射电子显微镜和zeta电位分析等标准表征工具,为磁性纳米粒子的客户和研究人员提供这些氧化铁纳米粒子产品的概述。此外,研究了这些氧化铁纳米粒子在水溶液中在低频和高频交变磁场下的动态磁响应,给出了表征海洋纳米技术公司磁性纳米粒子的标准化操作程序,从而为不同应用提供最佳的磁性纳米粒子。
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