二硫代氨基甲酸盐对大鼠扑热息痛和胆红素胆汁排泄的影响。
Influence of dithiocarb on the biliary excretion of paracetamol and bilirubin in rats.
作者信息
Siegers C P
出版信息
Experientia. 1978 Oct 15;34(10):1318-9. doi: 10.1007/BF01981443.
PMID:216574
Abstract
In bile-fistula rats, the biliary elimination of conjugated paracetamol and conjugated bilirubin is diminished by simultaneous administration of dithiocarb. This dithiocarb effect could be the result of the interference with the glucuronidation of the compounds.
摘要
在胆瘘大鼠中，同时给予二硫代氨基甲酸盐会减少结合型对乙酰氨基酚和结合型胆红素的胆汁排泄。这种二硫代氨基甲酸盐效应可能是由于干扰了这些化合物的葡萄糖醛酸化作用所致。
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