单次经皮注射基质细胞衍生因子-1可诱导小鼠闭合性胫骨骨折模型的骨修复。
Single percutaneous injection of stromal cell-derived factor-1 induces bone repair in mouse closed tibial fracture model.
作者信息
Li Xin, Gao Zhongli, Wang Jincheng
机构信息
Department of Orthopedic Surgery, Jilin University/China-Japan Union Hospital, Changchun, Jilin Province, China.
出版信息
Orthopedics. 2011 Jun;34(6):450. doi: 10.3928/01477447-20110427-19.
PMID:21661676
Abstract
Stromal cell-derived factor-1 is a dominant chemokine in bone marrow that is known to be involved in inflammatory diseases, including rheumatoid arthritis. Its role in bone repair has recently been demonstrated. The purpose of this study was to investigate the role of extraneous stromal cell-derived factor-1 in fracture healing.
摘要
基质细胞衍生因子-1是骨髓中一种主要的趋化因子，已知其参与包括类风湿性关节炎在内的炎症性疾病。最近已证实其在骨修复中的作用。本研究的目的是探讨外源性基质细胞衍生因子-1在骨折愈合中的作用。
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